GlobalRPh RX List - PONVORY
- Product / population
- Ponesimod - PONVORY tablets; selected renal passages, not a complete prescribing monograph.
- Renal measure
- Cockcroft-Gault creatinine clearance (CrCl), mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No renal dosage adjustment is needed. Adult moderate (Cockcroft-Gault CrCl 30-59 mL/min) and severe (<30) groups had no significant exposure changes compared with normal renal function. Dialysis effects have not been studied. Retain the complete initiation/titration and cardiac/infection precautions; this renal statement does not establish a dialysis supplement or remove nonrenal eligibility requirements.