GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Product-specific reference

Paricalcitol - ZEMPLAR IV injection

Read renal action and limits
Local official-label summarySource retrieved 2026-11-07See the evidence for this drug2 sources available - open source summaries, references and comparisons

ZEMPLAR injection / Paricalcitol / paricalcitol IV

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)
Review first - source-specific qualification

Directory formulation wording is unreliable for ZEMPLAR

The retained index calls this product tablets, while the selected monograph describes IV dosing. Adult and pediatric titration increments must also remain separate.

Before applying: Confirm IV product and adult scope. Do not apply this regimen to oral capsules or children.

Evidence for this qualification

Selected-source comparison; independent clinician adjudication pending.

Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist

Choose a source to read (2)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Official source

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titration

This source only - not a merged recommendation

What matters first

Product: Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Renal action / finding
Adult start 0.04-0.1 mcg/kg IV during dialysis.
Evidence or dialysis limit
Adult IV only. The pediatric 0.04 mcg/kg increment is NOT the adult titration increment.
Monitoring / application
Use the full PTH-response table; monitor calcium and PTH.

Selected-section summary, not a complete monograph. Independent clinician review remains pending. Read the exact renal measure, dates and full source below.

Product / population
Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.
Renal measure
Dialysis-dependent CKD; titration uses calcium and intact PTH, not a CrCl dose band
Source revision
08/2024
Retrieved
2026-11-07 (not the revision date)
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

Adult IV only. The pediatric 0.04 mcg/kg increment is NOT the adult titration increment.

Sections 2.1 and 2.2, adult titration Table 1

Sections 2.1 and 2.2, adult titration Table 1
SituationSource-specific guidance
Adult start0.04-0.1 mcg/kg IV; no more often than every other day.
Adult upward titration when indicated2-4 mcg every 2-4 weeks; follow the PTH response table.
Laboratory safetyCalcium frequently; PTH every 2-4 weeks after dose changes.
Read the retained text before reformatting

Before starting, calcium must not exceed the normal upper limit. Adult starting dose: 0.04-0.1 mcg/kg IV during dialysis, no more often than every other day. If PTH remains above target and rises or falls less than 30%, increase by 2-4 mcg every 2-4 weeks. A 30-60% fall above target supports no change; a greater than 60% fall calls for reduction using clinical judgment. Maximum adult daily dose is 0.24 mcg/kg. Follow calcium frequently and PTH every 2-4 weeks after starting or adjusting. Reduce/hold for persistent low PTH or high calcium.

Source revision: 08/2024 | Retrieved: 2026-11-07. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7259652f-81bc-4ad1-bba5-d01f9fac1b80

Scope: Selected named sections summarized; not a complete monograph or independent clinician approval. GlobalRPh v7.4.

Full source card / provenance

All sources, comparison tools and evidence navigation
Source-specific interpretation

What the dialysis evidence actually supports

Removal information alone does not define a maintenance dose, supplemental dose or dialysis schedule. A reported regimen still requires its product, indication, renal measure and dialysis assumptions to match the patient.

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titration

Source retrieved 2026-11-07 - confirm current applicability

A regimen is reported in selected content

Read the source and its limits

ZEMPLAR: selected adult IV passages, not directory tablet wording

Source retrieved 2026-11-07 - confirm current applicability

A regimen is reported in selected content

Read the source and its limits

These manual classifications apply only to the identified selected sections, not every retained source or the entire prescribing information. They are not dosing clearance.

Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

Official product label

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titration

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

Adult IV only. The pediatric 0.04 mcg/kg increment is NOT the adult titration increment.

Dialysis evidence: A regimen is reported in selected content

Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Renal method: Dialysis-dependent CKD; titration uses calcium and intact PTH, not a CrCl dose band
Retrieved: 2026-11-07

Read local renal resultOpen this source quick answerOpen original reference
GlobalRPh RX List

ZEMPLAR: selected adult IV passages, not directory tablet wording

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

Confirm product, indication, renal measure and dialysis modality before applying.

Dialysis evidence: A regimen is reported in selected content

Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Renal method: Dialysis and laboratory-directed adult IV dosing
Retrieved: 2026-11-07

Read local renal resultOpen this source quick answerOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-specific review points

Directory formulation wording is unreliable for ZEMPLAR

Read the attributed comparison notes and source cards below. No conflict has been silently adjudicated.

Source-quality holds
Find text within this drug
Find a term without leaving this drug

Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

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All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

Open / share selected sources
Jump to renal guidanceRead 1 difference / caution notesClinician guide

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Source scope / renal recommendation differences

Directory formulation wording is unreliable for ZEMPLAR

The retained index calls this product tablets, while the selected monograph describes IV dosing. Adult and pediatric titration increments must also remain separate.

How to use this: Confirm IV product and adult scope. Do not apply this regimen to oral capsules or children.

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titrationZEMPLAR: selected adult IV passages, not directory tablet wordingParicalcitol - ZEMPLAR oral capsules, adult renal regimens

Selected-source comparison; independent clinician adjudication pending.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
Official source

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titration

Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Method: Dialysis-dependent CKD; titration uses calcium and intact PTH, not a CrCl dose band

Read this complete source summary
Rxlist source

ZEMPLAR: selected adult IV passages, not directory tablet wording

Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Method: Dialysis and laboratory-directed adult IV dosing

Selected renal sectionsRead this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeZEMPLAR IV: adult dialysis dosing and laboratory-directed titrationZEMPLAR: selected adult IV passages, not directory tablet wording
Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

An RX mirror and its underlying label are not independent clinical confirmations.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7259652f-81bc-4ad1-bba5-d01f9fac1b80

Product identity and scope

Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

RDM71-paricalcitol-zemplar-iv-scope · Source section: Product identity and scopeRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

ZEMPLAR IV: adult dialysis dosing and laboratory-directed titration

Open original reference

Open / share this exact local source

DailyMed / product prescribing information · Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Renal method: Dialysis-dependent CKD; titration uses calcium and intact PTH, not a CrCl dose band
Source date: 08/2024
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

Adult IV only. The pediatric 0.04 mcg/kg increment is NOT the adult titration increment.

Dialysis evidence: A regimen is reported in selected content

Selected named sections summarized; not a complete monograph or independent clinician approval.

Sections 2.1 and 2.2, adult titration Table 1

Sections 2.1 and 2.2, adult titration Table 1
SituationSource-specific guidance
Adult start0.04-0.1 mcg/kg IV; no more often than every other day.
Adult upward titration when indicated2-4 mcg every 2-4 weeks; follow the PTH response table.
Laboratory safetyCalcium frequently; PTH every 2-4 weeks after dose changes.
Read the retained text before reformatting

Before starting, calcium must not exceed the normal upper limit. Adult starting dose: 0.04-0.1 mcg/kg IV during dialysis, no more often than every other day. If PTH remains above target and rises or falls less than 30%, increase by 2-4 mcg every 2-4 weeks. A 30-60% fall above target supports no change; a greater than 60% fall calls for reduction using clinical judgment. Maximum adult daily dose is 0.24 mcg/kg. Follow calcium frequently and PTH every 2-4 weeks after starting or adjusting. Reduce/hold for persistent low PTH or high calcium.

RDM71-paricalcitol-zemplar-iv-label-1 · Source locator: Sections 2.1 and 2.2, adult titration Table 1

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7259652f-81bc-4ad1-bba5-d01f9fac1b80
Retrieved
2026-11-07
Renal-function method
Dialysis-dependent CKD; titration uses calcium and intact PTH, not a CrCl dose band
Source date/version
08/2024
Hash meaning
Locally authored summary text; not original source HTML, XML or PDF bytes
Local summary SHA-256
5eff54a83e541c49f5043aaf16afe49e4204e55c93e9caadd4e514408701884f
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

ZEMPLAR: selected adult IV passages, not directory tablet wording

Open original reference

Open / share this exact local source

GlobalRPh RX List / label mirror · Adult IV ZEMPLAR for secondary hyperparathyroidism in CKD on dialysis. Not oral capsules, and not a pediatric titration protocol.

Renal method: Dialysis and laboratory-directed adult IV dosing
Source date: Not established in reviewed passage
Retrieved: 2026-11-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

Confirm product, indication, renal measure and dialysis modality before applying.

Dialysis evidence: A regimen is reported in selected content

Selected named sections summarized; not a complete monograph or independent clinician approval.

Selected renal sections

The named adult IV section gives 0.04-0.1 mcg/kg at dialysis, not more often than every other day, with adult increases of 2-4 mcg at 2-4-week intervals when indicated by PTH response. The directory tablet description does not match this IV content. Do not substitute this guidance for oral paricalcitol.

RDM71-paricalcitol-zemplar-iv-rx-1 · Source locator: Selected renal sections

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/zemplar-drug/
Retrieved
2026-11-07
Renal-function method
Dialysis and laboratory-directed adult IV dosing
Source date/version
Not established in reviewed passage
Hash meaning
Locally authored summary text; not original source HTML, XML or PDF bytes
Local summary SHA-256
ed3986f09d39c1c3e19411dca78c99f76a985253e1c23bea4f9aabaa1ccad292

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7259652f-81bc-4ad1-bba5-d01f9fac1b80
Source retrieval
2026-11-07. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
4fe425b389429cf0dfba66eaba838a4f025d2b468b77bd34936c855132fc3314
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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