GlobalRPh RX List - Yorvipath
- Product / population
- Adult product-specific renal information; not a complete prescribing regimen.
- Renal measure
- Indexed eGFR, mL/min/1.73 m2.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No renal dose adjustment is required for eGFR at least 15 mL/min/1.73 m2. The source notes that its single-dose renal study did not find a clinically important exposure difference, but patients who had both hypoparathyroidism and severe renal impairment were not studied. This does not establish dosing below eGFR 15 or on dialysis. Continue the product-specific calcium-based titration and monitoring requirements.