Oxycodone/acetaminophen extended-release (XARTEMIS XR)

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Renal guidance at a glance

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Rxlist source

GlobalRPh RX List - Xartemis XR

Product / population: Adult product-specific renal information; not a complete prescribing regimen.
Renal measure: CrCl below 60 mL/min in supporting oxycodone data.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

In renal impairment, the product subsection directs starting with one tablet and adjusting as needed, with close monitoring for respiratory depression. The supporting oxycodone data define impairment as CrCl below 60 mL/min; the fixed-combination pharmacokinetics were not studied in this population. The selected instruction alone is not a complete prescription: confirm the product strength, interval, maximum acetaminophen exposure and complete opioid precautions before ordering.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/xartemis-xr-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Source-first renal review

Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - Xartemis XR

Qualitative renal precaution. No complete numerical renal schedule is supplied by this selected finding.

Adult product-specific renal information; not a complete prescribing regimen.

Renal method: CrCl below 60 mL/min in supporting oxycodone data.
Retrieved: 2026-09-07

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Renal-context checklist: population, kidney trend and dialysis

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Population Kidney-function trend Renal replacement setting

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

Rxlist source

GlobalRPh RX List - Xartemis XR

Adult product-specific renal information; not a complete prescribing regimen.

Method: CrCl below 60 mL/min in supporting oxycodone data.

Renal dosing, restrictions and evidence limits Read this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

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Original content / product scope GlobalRPh RX List - Xartemis XR

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/xartemis-xr-drug/

Exact product and population

Adult product-specific renal information; not a complete prescribing regimen.

RDM34-SCOPE-oxycodone-acetaminophen-xartemis-xr · Source section: Selected source product scopeRenal section finder

Locally imported selected renal sections

GlobalRPh RX List renal information

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GlobalRPh RX List - Xartemis XR

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GlobalRPh-hosted RX List · Adult product-specific renal information; not a complete prescribing regimen.

Renal method: CrCl below 60 mL/min in supporting oxycodone data.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Qualitative renal precaution. No complete numerical renal schedule is supplied by this selected finding.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM34-rxlist-xartemis-xr-drug-C1 · Source locator: Dosage: renal impairment; use in specific populations and clinical pharmacology.

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/xartemis-xr-drug/
Retrieved: 2026-09-07
Renal-function method: CrCl below 60 mL/min in supporting oxycodone data.
Source date/version: Source revision date not established in selected retrieval.
Hash meaning: SHA-256 of local authored summary only, not original HTML, PDF or SPL bytes.
Local summary SHA-256: 96fc063ebfa9fdb4d98c8165a6e0208c507f4a2f5524212688d087f31de104ae

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/xartemis-xr-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: 683bb14dd8801e8c99ea2f4e755ba01976eb538e9b08fae7b6c44c671980305e
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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