GlobalRPh Renal Dosing Masterv6.8
Product-specific reference

Oxaprozin oral caplets (Daypro)

Local official-label summarySource retrieved 2026-10-02See the evidence for this drug2 sources available - open source summaries, references and comparisons

oxaprozin / Daypro

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)
Review first - source-specific qualification

Before use: Oxaprozin oral caplets (Daypro)

Do not treat 600 mg daily as permission to use an NSAID in advanced kidney disease.

Before applying: First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Evidence for this qualification

Selected source reconciliation only; independent clinician adjudication pending.

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

Choose a source to read (2)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Official source

Oxaprozin oral caplets (Daypro) - selected label sections

Product / population
DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.
Renal measure
Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Source revision
11/2024
Retrieved
2026-10-02 (not the revision date)

The official product label and its RX mirror are one underlying evidence family, not two independent clinical validations. Confirm the current exact product label before prescribing.

Renal guidance and important limits

Limits that apply to these rows

No numerical severe-impairment cutoff is assigned in this summary. Correct hypovolemia and monitor renal function; consider hyperkalemia risk.

Use the lowest effective dose for the shortest necessary duration. Cardiovascular and gastrointestinal boxed warnings remain applicable.

Oxaprozin oral caplets (Daypro) - selected renal instructions
Renal settingSource-specific action and limits
Advanced renal diseaseAvoid unless anticipated benefit outweighs worsening-renal-function risk. This warning still applies to the reduced starting dose.
Severe renal impairment or dialysis, when treatment is justifiedStart 600 mg orally once daily. Only if symptom relief is inadequate, cautiously increase to 1200 mg with close monitoring.
Read the retained text before reformatting
Renal settingSource-specific action and limits
Advanced renal diseaseAvoid unless anticipated benefit outweighs worsening-renal-function risk. This warning still applies to the reduced starting dose.
Severe renal impairment or dialysis, when treatment is justifiedStart 600 mg orally once daily. Only if symptom relief is inadequate, cautiously increase to 1200 mg with close monitoring.

No numerical severe-impairment cutoff is assigned in this summary. Correct hypovolemia and monitor renal function; consider hyperkalemia risk.

Use the lowest effective dose for the shortest necessary duration. Cardiovascular and gastrointestinal boxed warnings remain applicable.

Source revision: 11/2024 | Retrieved: 2026-10-02. Retrieval date is not the revision date.

Source: https://labeling.pfizer.com/ShowLabeling.aspx?id=552

Scope: Selected renal sections summarized locally. Not a complete monograph or independent clinical approval. GlobalRPh v6.8.

Full source card / provenance

All sources, comparison tools and evidence navigation
Added / rechecked in v6.8

Read source findings

Read source-specific summaries and their qualifications. Retrieval date is not label revision date. Recent review does not imply clinical approval.

Official

Oxaprozin oral caplets (Daypro) - selected label sections

Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

Retrieved: 2026-10-02
Source revision: 11/2024

Renal measure: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.

Read this dated source finding
Rxlist

Oxaprozin oral caplets (Daypro) - RX mirror renal summary

Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

Retrieved: 2026-10-02
Source revision: 11/2024

Renal measure: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.

Read this dated source finding
See all retained evidence sources
Source-specific interpretation

What the dialysis evidence actually supports

Removal information alone does not define a maintenance dose, supplemental dose or dialysis schedule. A reported regimen still requires its product, indication, renal measure and dialysis assumptions to match the patient.

Oxaprozin oral caplets (Daypro) - selected label sections

Source retrieved 2026-10-02

A dialysis-population initial dose is reported; maintenance requires titration

Read the source and its limits

Oxaprozin oral caplets (Daypro) - RX mirror renal summary

Source retrieved 2026-10-02

A dialysis-population initial dose is reported; maintenance requires titration

Read the source and its limits

These manual classifications apply only to the identified selected sections, not every retained source or the entire prescribing information. They are not dosing clearance.

Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

Official product label

Oxaprozin oral caplets (Daypro) - selected label sections

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Renal method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Retrieved: 2026-10-02

Read local renal resultOpen original reference
GlobalRPh RX List

Oxaprozin oral caplets (Daypro) - RX mirror renal summary

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Renal method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Retrieved: 2026-10-02

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Find text within this drug
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Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

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All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

Open / share selected sources
Jump to renal guidanceRead 1 difference / caution notesClinician guide

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
Official source

Oxaprozin oral caplets (Daypro) - selected label sections

DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.

Renal guidance and important limitsRead this complete source summary
Rxlist source

Oxaprozin oral caplets (Daypro) - RX mirror renal summary

DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.

Renal guidance and important limitsRead this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeOxaprozin oral caplets (Daypro) - selected label sectionsOxaprozin oral caplets (Daypro) - RX mirror renal summary
Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

The official product label and its RX mirror are one underlying evidence family, not two independent clinical validations. Confirm the current exact product label before prescribing.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://labeling.pfizer.com/ShowLabeling.aspx?id=552

Exact product and population

DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

RDM68-oxaprozin-daypro-d241a16537 · Source section: Selected primary product label: indications / formulationRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Oxaprozin oral caplets (Daypro) - selected label sections

Open original reference

Open / share this exact local source

Pfizer / DAYPRO prescribing information · DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Renal method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Source date: 11/2024
Retrieved: 2026-10-02

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

Selected renal sections summarized locally. Not a complete monograph or independent clinical approval.

Renal guidance and important limits

Limits that apply to these rows

No numerical severe-impairment cutoff is assigned in this summary. Correct hypovolemia and monitor renal function; consider hyperkalemia risk.

Use the lowest effective dose for the shortest necessary duration. Cardiovascular and gastrointestinal boxed warnings remain applicable.

Oxaprozin oral caplets (Daypro) - selected renal instructions
Renal settingSource-specific action and limits
Advanced renal diseaseAvoid unless anticipated benefit outweighs worsening-renal-function risk. This warning still applies to the reduced starting dose.
Severe renal impairment or dialysis, when treatment is justifiedStart 600 mg orally once daily. Only if symptom relief is inadequate, cautiously increase to 1200 mg with close monitoring.
Read the retained text before reformatting
Renal settingSource-specific action and limits
Advanced renal diseaseAvoid unless anticipated benefit outweighs worsening-renal-function risk. This warning still applies to the reduced starting dose.
Severe renal impairment or dialysis, when treatment is justifiedStart 600 mg orally once daily. Only if symptom relief is inadequate, cautiously increase to 1200 mg with close monitoring.

No numerical severe-impairment cutoff is assigned in this summary. Correct hypovolemia and monitor renal function; consider hyperkalemia risk.

Use the lowest effective dose for the shortest necessary duration. Cardiovascular and gastrointestinal boxed warnings remain applicable.

RDM68-oxaprozin-daypro-4eddc1c0d0 · Source locator: Sections 2.5 and 5.6; boxed warning

Source-specific limits

The official product label and its RX mirror are one underlying evidence family, not two independent clinical validations. Confirm the current exact product label before prescribing.

Source identity and provenance
Source family
product_label
Source
https://labeling.pfizer.com/ShowLabeling.aspx?id=552
Retrieved
2026-10-02
Renal-function method
Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Source date/version
11/2024
Hash meaning
Local authored summary; not source HTML/XML/PDF bytes
Local summary SHA-256
4eddc1c0d04e5a6617c4f6a3a2236a805aa2db3163409d27612649d4a73dc773
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

Oxaprozin oral caplets (Daypro) - RX mirror renal summary

Open original reference

Open / share this exact local source

GlobalRPh RX List / product-label mirror · DAYPRO 600 mg oral caplets. This selected renal summary is for adult osteoarthritis/rheumatoid arthritis use; pediatric weight-based dosing is not supplied here.

Renal method: Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Source date: 11/2024
Retrieved: 2026-10-02

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Before using this finding

First establish that use is justified despite the renal warning; then apply only the exact product-label instructions.

Dialysis evidence: A dialysis-population initial dose is reported; maintenance requires titration

Selected renal sections summarized locally. Not a complete monograph or independent clinical approval.

Renal guidance and important limits

The mirror repeats a 600 mg once-daily starting dose for severe renal impairment or dialysis, with a cautious increase to 1200 mg only for insufficient relief and close monitoring. It separately advises avoiding advanced renal disease unless benefit outweighs renal risk. These statements must be read together.

RDM68-oxaprozin-daypro-2ec99f8ce9 · Source locator: Named RX renal impairment, dosage and renal-warning sections

Source-specific limits

The official product label and its RX mirror are one underlying evidence family, not two independent clinical validations. Confirm the current exact product label before prescribing.

Source identity and provenance
Source family
product_label
Source
https://globalrph.com/rx-list/daypro-drug/
Retrieved
2026-10-02
Renal-function method
Qualitative severe renal impairment / dialysis; the selected dose paragraph does not define a numerical CrCl cutoff.
Source date/version
11/2024
Hash meaning
Local authored summary; not source HTML/XML/PDF bytes
Local summary SHA-256
2ec99f8ce942ef7e189c83bb82457aa294fd1a8ad27f2d250fcb76342c6a0513

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://labeling.pfizer.com/ShowLabeling.aspx?id=552
Source retrieval
2026-10-02. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
d241a1653748ab17f65cad64bba883749b3a07fb7abd6870c0339ea63a5099aa
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

Read the full coverage report