GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Olaparib tablets (Lynparza)

Local official-label summaryBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons

Lynparza

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Official source

Olaparib tablets (Lynparza) - selected U.S. label sections

Product / population
LYNPARZA oral tablets, not the historical capsule formulation.
Renal measure
Creatinine clearance in mL/min

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Renal dose comments

CrCl 51-80 mL/min does not require a renal dose adjustment. At CrCl 31-50, reduce the tablet dose to 200 mg twice daily. Data are absent for severe impairment or end-stage disease with CrCl at or below 30.

Formulation protection

Do not use a capsule-based regimen or assume capsule/tablet dose equivalence. This summary does not establish a dialysis dose.

Source revision: Revision not captured; retrieval date is not the revision date. | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa

Scope: Local label summary; independent clinical review pending. Not a two-source validated protocol. GlobalRPh v6.6.

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Official product label

Olaparib tablets (Lynparza) - selected U.S. label sections

LYNPARZA oral tablets, not the historical capsule formulation.

Renal method: Creatinine clearance in mL/min
Retrieved: 2026-09-05

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeOlaparib tablets (Lynparza) - selected U.S. label sections
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa

Product and population scope

LYNPARZA oral tablets, not the historical capsule formulation.

RDM32-olaparib-lynparza-tablets-scope · Source section: Editorial scope for the selected U.S. labelRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Olaparib tablets (Lynparza) - selected U.S. label sections

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U.S. product labeling / DailyMed · LYNPARZA oral tablets, not the historical capsule formulation.

Renal method: Creatinine clearance in mL/min
Source date: Revision not captured; retrieval date is not the revision date.
Retrieved: 2026-09-05

Local label summary; independent clinical review pending. Not a two-source validated protocol.

Renal dose comments

CrCl 51-80 mL/min does not require a renal dose adjustment. At CrCl 31-50, reduce the tablet dose to 200 mg twice daily. Data are absent for severe impairment or end-stage disease with CrCl at or below 30.

RDM32-olaparib-lynparza-tablets-1 · Source locator: 2.5; 8.6

Formulation protection

Do not use a capsule-based regimen or assume capsule/tablet dose equivalence. This summary does not establish a dialysis dose.

RDM32-olaparib-lynparza-tablets-2 · Source locator: 2; 8.6

Source-specific limits

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa
Retrieved
2026-09-05
DailyMed Set ID
741ff3e3-dc1a-45a6-84e5-2481b27131aa
Renal-function method
Creatinine clearance in mL/min
Source date/version
Revision not captured; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or a label PDF.
Local summary SHA-256
7f0213f055c0c9e023920343264450d3132c398021dbc4be1034787c575ba143

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
4bcbcaaa36129683f92ef655854f37dc2d333b38429b0a3bf8c2531d8fd5674a
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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