GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Nevirapine extended-release (VIRAMUNE XR)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Viramune XR

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Renal guidance at a glance

Cautions / source differences (1)

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Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

1 additional source qualifications - review before use
XR source calls for an immediate-release dialysis supplement

The XR page discusses an immediate-release post-dialysis supplement while explicitly stating that XR has not been studied in renal dysfunction. That is not direct validation of an extra XR tablet.

Before applying: Verify the established antiretroviral regimen, precise release form and specialist plan. Retain the below-threshold evidence gap and hepatic/rash precautions; do not substitute a release form based on the common ingredient.

Also check: XR source calls for an immediate-release dialysis supplement

Rxlist source

GlobalRPh RX List - Viramune XR

Product / population
VIRAMUNE XR source discusses an immediate-release supplement; XR renal data are absent.
Renal measure
CrCl at least 20 mL/min without dialysis; below 20 not evaluated.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The source states no adjustment at CrCl >=20 without dialysis, but also says VIRAMUNE XR itself has not been studied in renal dysfunction. For dialysis it specifically calls for an extra 200 mg of immediate-release VIRAMUNE after treatment, not an additional XR tablet. Below CrCl 20, pharmacokinetics have not been evaluated. Metabolite accumulation has uncertain significance. Keep this formulation and evidence limitation visible; the text is not proof of direct XR dialysis validation.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/viramune-xr-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - Viramune XR

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

VIRAMUNE XR source discusses an immediate-release supplement; XR renal data are absent.

Renal method: CrCl at least 20 mL/min without dialysis; below 20 not evaluated.
Retrieved: 2026-09-07

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Jump to renal guidanceRead 1 difference / caution notesClinician guide

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See source-specific renal methods and the clinical interpretation guide for the supporting context.

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Source differences and product cautions

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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

formulation evidence gap

XR source calls for an immediate-release dialysis supplement

The XR page discusses an immediate-release post-dialysis supplement while explicitly stating that XR has not been studied in renal dysfunction. That is not direct validation of an extra XR tablet.

How to use this: Verify the established antiretroviral regimen, precise release form and specialist plan. Retain the below-threshold evidence gap and hepatic/rash precautions; do not substitute a release form based on the common ingredient.

GlobalRPh RX List - Viramune XRNevirapine

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - Viramune XR
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/viramune-xr-drug/

Exact product and population

VIRAMUNE XR source discusses an immediate-release supplement; XR renal data are absent.

RDM40-SCOPE-nevirapine-viramune-xr · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Viramune XR

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GlobalRPh-hosted RX List · VIRAMUNE XR source discusses an immediate-release supplement; XR renal data are absent.

Renal method: CrCl at least 20 mL/min without dialysis; below 20 not evaluated.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The source states no adjustment at CrCl >=20 without dialysis, but also says VIRAMUNE XR itself has not been studied in renal dysfunction. For dialysis it specifically calls for an extra 200 mg of immediate-release VIRAMUNE after treatment, not an additional XR tablet. Below CrCl 20, pharmacokinetics have not been evaluated. Metabolite accumulation has uncertain significance. Keep this formulation and evidence limitation visible; the text is not proof of direct XR dialysis validation.

RDM40-rxlist-nevirapine-viramune-xr-34f2370591-C1 · Source locator: Selected renal dosing, renal impairment, toxicity and pharmacokinetic subsections as identified in the summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/viramune-xr-drug/
Retrieved
2026-09-07
Renal-function method
CrCl at least 20 mL/min without dialysis; below 20 not evaluated.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
7cae320ad9488851e1b477d544ab63e95467946ea0a500e0bdfd68246a109c27

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/viramune-xr-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
0c54ec95a7b2055f3974a9e21060f6955bad03dc17b8a12d6a1e9b6e0df7afb4
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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