GlobalRPh RX List - Vimovo
- Product / population
- VIMOVO fixed-dose naproxen/esomeprazole; renal restrictions are not removed by the acid-suppressant component.
- Renal measure
- Creatinine clearance below 30 mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
The source does not recommend this naproxen-containing product when CrCl is below 30. It does not offer a reduced-dose schedule that makes use in that population acceptable. Review NSAID renal and volume-status risks in the full product information. The combination's esomeprazole component is not a reason to disregard naproxen-related renal restrictions.