GlobalRPh RX List - XIFYRM
- Product / population
- XIFYRM meloxicam IV injection; not QMIIZ ODT or oral meloxicam tablets.
- Renal measure
- Source mild-impairment PK uses eGFR 60-90; moderate/severe categories are qualitative in the selected restriction.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Mild impairment: no dosage adjustment is necessary in the selected source. Moderate to severe renal insufficiency: XIFYRM is not recommended; it is contraindicated in this group when volume depletion creates a risk of renal failure. Correct hypovolemia before treatment and monitor kidney function in susceptible patients. Moderate and severe impairment were not adequately studied. Do not transfer the oral meloxicam hemodialysis ceiling to this IV formulation.