GlobalRPh RX List - XOLREMDI
- Product / population
- XOLREMDI oral capsules for WHIM syndrome from age 12; separate weight and interaction rules apply.
- Renal measure
- Cockcroft-Gault CrCl, mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No renal adjustment is recommended at CrCl 30 to <90 mL/min. Treatment is not recommended with severe impairment (15 to <30) or ESRD (<15); these groups were not studied. Use the weight-based product regimen and separately reconcile CYP3A/P-gp interactions. The renal statement does not waive those interaction-based modifications.