GlobalRPh RX List - Lutathera
- Product / population
- IV radiopharmaceutical; selected baseline renal guidance only, not on-treatment toxicity rules.
- Renal measure
- CrCl by Cockcroft-Gault, mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No baseline dose adjustment is recommended for CrCl 30 to 89 mL/min. Perform more frequent renal assessments because increased radiation exposure can increase toxicity, including renal toxicity. Baseline CrCl below 30 mL/min and end-stage renal disease have not been studied. The complete protocol also requires renal-protective administration and treatment-emergent toxicity rules, which are not replaced by this baseline statement.