GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
GlobalRPh source record

Lurasidone

Read renal action and limits
Local official-label summarySource retrieved 2026-09-05See the evidence for this drug3 sources available - open source summaries, references and comparisons

Latuda

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)

Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist

Choose a source to read (3)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

1 additional source qualifications - review before use
Latuda - product and source limitations

This includes both CrCl 30 to below 50 and CrCl below 30. Check interacting CYP3A4 drugs before titration.

Before applying: Apply only to the stated formulation, indication and renal population.

Also check: Latuda - product and source limitations

Rxlist source

Latuda - selected RX renal passage

Choose a product and source Product label All evidence
Product / population
Lurasidone (Latuda), adult oral tablets
Renal measure
Use the renal measure explicitly present in the RX passage.
Source revision
Mirror revision not established in the reviewed passage.
Retrieved
2026-11-07 (not the revision date)

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

This mirror and the underlying product label share a source family.

RX List: selected renal passage

The moderate and severe CrCl groups share a 20 mg/day starting dose and an 80 mg/day ceiling.

Source revision: Mirror revision not established in the reviewed passage. | Retrieved: 2026-11-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/latuda-drug/

Scope: Selected renal passages reviewed; independent clinician adjudication pending. GlobalRPh v7.4.

Full source card / provenance

All sources, comparison tools and evidence navigation
Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

Official product label

Latuda - labeled renal guidance

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Lurasidone (Latuda), adult oral tablets

Renal method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Retrieved: 2026-11-07

Read local renal resultOpen this source quick answerOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-specific review points

Latuda - product and source limitations

Read the attributed comparison notes and source cards below. No conflict has been silently adjudicated.

Source-quality holds
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Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

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All source summaries, original wording and provenance
Before applying a renal protocol

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No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

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Jump to renal guidanceRead 1 difference / caution notesClinician guide

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Source scope / renal recommendation differences

Latuda - product and source limitations

This includes both CrCl 30 to below 50 and CrCl below 30. Check interacting CYP3A4 drugs before titration.

How to use this: Apply only to the stated formulation, indication and renal population.

Latuda - labeled renal guidanceLatuda - selected RX renal passage

Selected renal passages reviewed; independent clinician adjudication pending.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeLatuda - labeled renal guidanceLatuda - selected RX renal passage
Choose two source checkboxes below.
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

Historical dose ceilings and approved-use descriptions are preserved, not asserted to be current FDA labeling.

Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. Read the original source for its complete context: https://globalrph.com/renal/lurasidone/

Mechanism and historical indication context

The mechanism is unknown; central dopamine D2 and serotonin 5-HT2A antagonism is proposed. The source describes adult schizophrenia efficacy in four 6-week studies and states that efficacy beyond 6 weeks had not been established in that labeling context. Reevaluate patients receiving extended treatment.

GRPH-lurasidone-01 · Source section: Mechanism and historical indication contextRenal section finder

Usual Dosing (Adults)

Start 40 mg once daily without initial titration. The historical source reports effectiveness from 40-120 mg/day, no additional benefit at 120 mg with more adverse reactions, and a maximum recommended dose of 80 mg/day. Take with food of at least 350 calories.

GRPH-lurasidone-02 · Source section: Usual Dosing (Adults)Renal section finder

Renal and hepatic dosing

CrCl at least 10 but below 50 mL/min: maximum 40 mg/day in this historical source. After a single 40 mg dose, Cmax increased 40%, 92% and 54% in mild, moderate and severe impairment; AUC increased 53%, 91% and approximately 2-fold respectively.

Moderate/severe hepatic impairment: source maximum 40 mg/day.

GRPH-lurasidone-03 · Source section: Renal and hepatic dosingRenal section finder

Interaction comments

With a moderate CYP3A4 inhibitor such as diltiazem: source maximum 40 mg/day. Do not use with a strong CYP3A4 inhibitor such as ketoconazole or a strong inducer such as rifampin.

GRPH-lurasidone-04 · Source section: Interaction commentsRenal section finder

Hemodialysis

No additional hemodialysis recommendation was present under this heading in the retrieved source.

GRPH-lurasidone-05 · Source section: HemodialysisRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Latuda - labeled renal guidance

Open original reference

Open / share this exact local source

DailyMed / product prescribing information · Lurasidone (Latuda), adult oral tablets

Renal method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date: DailyMed SPL version 37, effective 2025-01-31; posted Jan 14, 2026
Retrieved: 2026-11-07

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 2.4 and 8.6

At CrCl below 50 mL/min, start at 20 mg daily and limit the dose to 80 mg daily. This includes both CrCl 30 to below 50 and CrCl below 30. Check interacting CYP3A4 drugs before titration.

RDM73-latuda-official-1 · Source locator: Renal guidance: 2.4 and 8.6

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=afad3051-9df2-4c54-9684-e8262a133af8
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source date/version
DailyMed SPL version 37, effective 2025-01-31; posted Jan 14, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
450697bce8104021de1ec244c60bce421171989b2cce3b3a7b342eef5eee00c7
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

Latuda - selected RX renal passage

Open original reference

Open / share this exact local source

GlobalRPh RX List / product-label mirror · Lurasidone (Latuda), adult oral tablets

Renal method: Use the renal measure explicitly present in the RX passage.
Source date: Mirror revision not established in the reviewed passage.
Retrieved: 2026-11-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

RX List: selected renal passage

The moderate and severe CrCl groups share a 20 mg/day starting dose and an 80 mg/day ceiling.

RDM73-latuda-rxlist-1 · Source locator: RX List: selected renal passage

Source-specific limits

This mirror and the underlying product label share a source family.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/latuda-drug/
Retrieved
2026-11-07
Renal-function method
Use the renal measure explicitly present in the RX passage.
Source date/version
Mirror revision not established in the reviewed passage.
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
ae0ea5dfcd085188978db1e5b73671a14daa96abc312099ac2de47a050e76004

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/lurasidone/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
08a4657dce5e70786b8f5d6aaf2f48d4ca3a1111d2f0db637ded71391c77e83d
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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