GlobalRPh RX List - Qbrelis
- Product / population
- QBRELIS 1 mg/mL oral solution. Numeric doses here are adult doses; pediatric restriction is separately labeled.
- Renal measure
- Adult CrCl, mL/min; pediatric indexed GFR, mL/min/1.73 m2.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Adults: no renal reduction is required at CrCl above 30 mL/min. At CrCl 10-30, start at half the usual indication-specific dose: hypertension 5 mg daily; systolic heart failure or acute MI 2.5 mg daily. At CrCl below 10 or with hemodialysis, the starting dose is 2.5 mg daily. Titrate to response and tolerability; the renal subsection permits up to 40 mg daily. Pediatric hypertension has separate weight-based instructions; the source does not recommend use below age 6 or at pediatric GFR below 30 mL/min/1.73 m2. Adult dose bands must not be used as a pediatric prescription.