GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Lisdexamfetamine (VYVANSE)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Vyvanse

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Renal guidance at a glance

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Rxlist source

GlobalRPh RX List - Vyvanse

Product / population
VYVANSE renal maximums; apply only with the correct indication and age-specific treatment plan.
Renal measure
Indexed GFR in mL/min/1.73 m2.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

At GFR 15 to below 30, do not exceed 50 mg once daily. With ESRD below 15, the maximum is 30 mg once daily. These are maximums, not starting doses. Lisdexamfetamine and dextroamphetamine are not dialyzable. Urine-acidifying and alkalinizing agents can alter amphetamine exposure; account for those interactions rather than treating the renal maximum as sufficient monitoring.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/vyvanse-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Source-first renal review

Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - Vyvanse

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

VYVANSE renal maximums; apply only with the correct indication and age-specific treatment plan.

Renal method: Indexed GFR in mL/min/1.73 m2.
Retrieved: 2026-09-07

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Jump to renal guidanceClinician guide

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Renal-context checklist: population, kidney trend and dialysis

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See source-specific renal methods and the clinical interpretation guide for the supporting context.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - Vyvanse
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/vyvanse-drug/

Exact product and population

VYVANSE renal maximums; apply only with the correct indication and age-specific treatment plan.

RDM40-SCOPE-lisdexamfetamine-vyvanse · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Vyvanse

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GlobalRPh-hosted RX List · VYVANSE renal maximums; apply only with the correct indication and age-specific treatment plan.

Renal method: Indexed GFR in mL/min/1.73 m2.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

At GFR 15 to below 30, do not exceed 50 mg once daily. With ESRD below 15, the maximum is 30 mg once daily. These are maximums, not starting doses. Lisdexamfetamine and dextroamphetamine are not dialyzable. Urine-acidifying and alkalinizing agents can alter amphetamine exposure; account for those interactions rather than treating the renal maximum as sufficient monitoring.

RDM40-rxlist-lisdexamfetamine-vyvanse-3b1af44cd4-C1 · Source locator: Selected renal dosing, renal impairment, toxicity and pharmacokinetic subsections as identified in the summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/vyvanse-drug/
Retrieved
2026-09-07
Renal-function method
Indexed GFR in mL/min/1.73 m2.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
0eb0aaed33fbb2c8bfa50c9a29569e7ca1831c0720d8c424a0527383348120cf

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/vyvanse-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
fab4da45de4121b5cfc1488967fe3559877ad3fee1d2fc75cdbdcb7ee74f5d77
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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