GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Lenalidomide capsules (indication-specific adult renal table)

Revlimid

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Renal guidance at a glance

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Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Official source

Lenalidomide capsules (indication-specific adult renal table) - selected U.S. label sections

Product / population
Selected U.S. lenalidomide capsule label. MM=myeloma; MCL=mantle-cell lymphoma; FL=follicular lymphoma; MZL=marginal-zone lymphoma; MDS=myelodysplastic syndromes.
Renal measure
Cockcroft-Gault creatinine clearance in mL/min

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Renal dose table - keep the indication-specific cycle

CrClMM/MCL combinationFL/MZL combinationMM post-transplant maintenance or MDS
30-60 mL/min10 mg once daily10 mg once daily5 mg once daily
Below 30, without dialysis15 mg every other day5 mg once daily2.5 mg once daily
Below 30, requiring dialysis5 mg once daily5 mg once daily2.5 mg once daily

On dialysis days, administer after dialysis. Apply these doses within the indicated treatment cycle, not an invented continuous schedule.

Subsequent adjustment

For MM combination therapy at CrCl 30-60, the label permits considering 15 mg after two cycles if 10 mg was tolerated without dose-limiting toxicity. Subsequent changes depend on indication and tolerability.

Source revision: Revision not captured; retrieval date is not the revision date. | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2166bbdf-eb12-4564-b9e4-b63ca21312bc

Scope: Local label summary; independent clinical review pending. Not a two-source validated protocol. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

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Official product label

Lenalidomide capsules (indication-specific adult renal table) - selected U.S. label sections

Selected U.S. lenalidomide capsule label. MM=myeloma; MCL=mantle-cell lymphoma; FL=follicular lymphoma; MZL=marginal-zone lymphoma; MDS=myelodysplastic syndromes.

Renal method: Cockcroft-Gault creatinine clearance in mL/min
Retrieved: 2026-09-05

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

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Renal-context checklist: population, kidney trend and dialysis

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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2166bbdf-eb12-4564-b9e4-b63ca21312bc

Product and population scope

Selected U.S. lenalidomide capsule label. MM=myeloma; MCL=mantle-cell lymphoma; FL=follicular lymphoma; MZL=marginal-zone lymphoma; MDS=myelodysplastic syndromes.

RDM32-lenalidomide-capsules-scope · Source section: Editorial scope for the selected U.S. labelRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Lenalidomide capsules (indication-specific adult renal table) - selected U.S. label sections

Open original reference

Open / share this exact local source

U.S. product labeling / DailyMed · Selected U.S. lenalidomide capsule label. MM=myeloma; MCL=mantle-cell lymphoma; FL=follicular lymphoma; MZL=marginal-zone lymphoma; MDS=myelodysplastic syndromes.

Renal method: Cockcroft-Gault creatinine clearance in mL/min
Source date: Revision not captured; retrieval date is not the revision date.
Retrieved: 2026-09-05

Local label summary; independent clinical review pending. Not a two-source validated protocol.

Renal dose table - keep the indication-specific cycle

CrClMM/MCL combinationFL/MZL combinationMM post-transplant maintenance or MDS
30-60 mL/min10 mg once daily10 mg once daily5 mg once daily
Below 30, without dialysis15 mg every other day5 mg once daily2.5 mg once daily
Below 30, requiring dialysis5 mg once daily5 mg once daily2.5 mg once daily

On dialysis days, administer after dialysis. Apply these doses within the indicated treatment cycle, not an invented continuous schedule.

RDM32-lenalidomide-capsules-1 · Source locator: 2.6, Table 3; 2.1-2.4

Subsequent adjustment

For MM combination therapy at CrCl 30-60, the label permits considering 15 mg after two cycles if 10 mg was tolerated without dose-limiting toxicity. Subsequent changes depend on indication and tolerability.

RDM32-lenalidomide-capsules-2 · Source locator: 2.6

Source-specific limits

Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.

Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2166bbdf-eb12-4564-b9e4-b63ca21312bc
Retrieved
2026-09-05
DailyMed Set ID
2166bbdf-eb12-4564-b9e4-b63ca21312bc
Renal-function method
Cockcroft-Gault creatinine clearance in mL/min
Source date/version
Revision not captured; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or a label PDF.
Local summary SHA-256
7c269d2b09efff995cfbb1e3157e46a7b25b20ad520371073d96304a2e59a949

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2166bbdf-eb12-4564-b9e4-b63ca21312bc
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
3902ce35edab0fa9eff9052001e8d46566f05bc12a83664036eac0e39d866377
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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