GlobalRPh RX List - SOMATULINE DEPOT
- Product / population
- Lanreotide - SOMATULINE DEPOT; selected renal source sections only, not a complete prescribing monograph.
- Renal measure
- Creatinine clearance (CrCl), mL/min; selected passage does not establish an estimating equation.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For acromegaly with CrCl <60 mL/min, start 60 mg by deep subcutaneous injection every four weeks for three months, then adjust. Use caution before extending a 120-mg dose to six- or eight-week intervals in moderate/severe impairment. In GEP-NET, mild/moderate impairment did not affect clearance during 120-mg treatment, but severe impairment was not studied. The acromegaly starting reduction is not an established GEP-NET renal regimen.
Source: https://globalrph.com/rx-list/somatuline-depot-drug/