GlobalRPh RX List - HUMULIN R U-100
- Product / population
- HUMULIN R regular human insulin U-100; not U-500 or a premixed insulin.
- Renal measure
- Qualitative renal impairment; glucose and potassium monitoring.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Renal impairment may require insulin dose reduction and more frequent glucose checks. The source gives no fixed percentage reduction based on CrCl. With IV administration, potassium needs close monitoring because insulin can produce hypokalemia. Use the correct concentration and route; this renal precaution does not define a complete DKA, hyperkalemia or outpatient insulin protocol.