GlobalRPh RX List - HUMULIN N
- Product / population
- Subcutaneous NPH human insulin suspension; HUMULIN N
- Renal measure
- Individual glucose response and changing kidney function
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Renal pharmacokinetics and pharmacodynamics have not been specifically studied for HUMULIN N. Renal impairment increases hypoglycemia risk; more frequent blood-glucose monitoring and dose adjustment may be necessary.
Adjustments are individualized to metabolic need, intake, activity, intercurrent illness and changes in renal function. The source does not supply a numeric renal reduction, a universal dialysis-day rule, or permission to interchange NPH with premixed or other basal insulins.