GlobalRPh RX List - IMKELDI
- Product / population
- IMKELDI imatinib oral solution, 80 mg/mL; adult renal dose instructions. Indication-specific baseline doses remain necessary.
- Renal measure
- CrCl in mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For CrCl 20-39 mL/min, reduce the recommended starting dose by 50%; subsequent increases depend on tolerability, and doses above 400 mg/day are not recommended. At CrCl 40-59 mL/min, doses above 600 mg/day are not recommended. Use caution in severe impairment. These limits do not supply one universal oncology dose or a pediatric renal regimen. Monitor kidney function during treatment.