GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Ibuprofen / famotidine fixed combination - DUEXIS

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

DUEXIS

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Rxlist source

GlobalRPh RX List - DUEXIS

Product / population
Adult fixed-dose oral ibuprofen/famotidine tablets; not separately titratable components.
Renal measure
CrCl in mL/min; renal function and potassium monitoring.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The fixed combination is not recommended at CrCl below 50 mL/min. Reduced renal clearance of famotidine can increase central nervous system adverse effects; the NSAID component adds renal injury risk. Correct volume depletion and monitor renal function and potassium in susceptible patients. Do not assume that gastroprotection removes NSAID renal risk or that an independently reduced famotidine dose can be delivered using this fixed tablet.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/duexis-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - DUEXIS

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Adult fixed-dose oral ibuprofen/famotidine tablets; not separately titratable components.

Renal method: CrCl in mL/min; renal function and potassium monitoring.
Retrieved: 2026-09-07

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Original content / product scopeGlobalRPh RX List - DUEXIS
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/duexis-drug/

Exact product and population

Adult fixed-dose oral ibuprofen/famotidine tablets; not separately titratable components.

RDM43-SCOPE-ibuprofen-famotidine-duexis · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - DUEXIS

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GlobalRPh-hosted RX List · Adult fixed-dose oral ibuprofen/famotidine tablets; not separately titratable components.

Renal method: CrCl in mL/min; renal function and potassium monitoring.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The fixed combination is not recommended at CrCl below 50 mL/min. Reduced renal clearance of famotidine can increase central nervous system adverse effects; the NSAID component adds renal injury risk. Correct volume depletion and monitor renal function and potassium in susceptible patients. Do not assume that gastroprotection removes NSAID renal risk or that an independently reduced famotidine dose can be delivered using this fixed tablet.

RDM43-rxlist-ibuprofen-famotidine-duexis-1572238d0f-C1 · Source locator: Selected Dosage / Renal Impairment / Warnings sections; see source-specific qualifications in this summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/duexis-drug/
Retrieved
2026-09-07
Renal-function method
CrCl in mL/min; renal function and potassium monitoring.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
d36bb8f35e910a3befc11e90fbb85186da517f87c382a5443d9a2411cefff313

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/duexis-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
19ab4e6e37abda9f8105fbdeebcf616144381de4819a06bfbbfe96fec9d2ec51
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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