Hydromorphone immediate-release tablets - selected U.S. label sections
- Product / population
- Selected U.S. hydromorphone immediate-release oral tablet label. Not extended-release tablets, injection or an opioid conversion calculator.
- Renal measure
- Renal-impairment severity; selected recommendation does not assign a numeric cutoff.
Selected renal sections only, not a complete monograph. Exact product, indication, patient population, renal method and all other contraindications/interactions remain controlling.
Second independent renal reference and clinician adjudication remain pending; no all-indication, dialysis or pediatric dose may be inferred from an omitted field.
Renal dose reduction
For renal impairment, initiate at one-quarter to one-half of the usual starting dose, according to the degree of impairment. Carefully titrate and reassess for adverse effects. The starting milligram dose also depends on prior opioid exposure and the clinical setting.
Important boundary
Do not use this fractional recommendation to calculate a cross-route or extended-release conversion. No dialysis supplemental dose is derived here.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f778dfab-e109-428e-b1b7-4dfb1b8293e4