GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Hydrocodone/ibuprofen - VICOPROFEN

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

VICOPROFEN

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Rxlist source

GlobalRPh RX List - VICOPROFEN

Product / population
Oral hydrocodone/ibuprofen combination; not single-agent hydrocodone
Renal measure
Qualitative advanced renal disease; no fixed CrCl combination dose

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The source does not recommend VICOPROFEN in advanced renal disease because controlled clinical data are unavailable. If treatment must be initiated, close renal-function monitoring is advised. Ibuprofen-related renal decompensation is a particular concern with impaired kidney function, heart failure, diuretic use or older age.

This fixed opioid/NSAID product cannot be treated as hydrocodone alone. Reducing the opioid component does not remove the NSAID renal risk, and the selected source provides no renal-adjusted combination regimen.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/vicoprofen-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - VICOPROFEN

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Oral hydrocodone/ibuprofen combination; not single-agent hydrocodone

Renal method: Qualitative advanced renal disease; no fixed CrCl combination dose
Retrieved: 2026-09-07

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Original content / product scopeGlobalRPh RX List - VICOPROFEN
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/vicoprofen-drug/

Exact product and population

Oral hydrocodone/ibuprofen combination; not single-agent hydrocodone

RDM38-SCOPE-hydrocodone-ibuprofen-vicoprofen · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - VICOPROFEN

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GlobalRPh-hosted RX List · Oral hydrocodone/ibuprofen combination; not single-agent hydrocodone

Renal method: Qualitative advanced renal disease; no fixed CrCl combination dose
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The source does not recommend VICOPROFEN in advanced renal disease because controlled clinical data are unavailable. If treatment must be initiated, close renal-function monitoring is advised. Ibuprofen-related renal decompensation is a particular concern with impaired kidney function, heart failure, diuretic use or older age.

This fixed opioid/NSAID product cannot be treated as hydrocodone alone. Reducing the opioid component does not remove the NSAID renal risk, and the selected source provides no renal-adjusted combination regimen.

RDM38-rxlist-hydrocodone-ibuprofen-vicoprofen-01e2918fbb-C1 · Source locator: Warnings: renal effects and advanced renal disease

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/vicoprofen-drug/
Retrieved
2026-09-07
Renal-function method
Qualitative advanced renal disease; no fixed CrCl combination dose
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
ea55b03363f848d1f2d95ba54531776d3912f9347aaaf53657358f0b4df8013e

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/vicoprofen-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
79078d6bcd595a8364a7dcfeced083b902df8b049ce2a6c1566a16dd2604d5de
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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