GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Guanfacine extended-release (INTUNIV)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Intuniv

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Renal guidance at a glance

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Rxlist source

GlobalRPh RX List - Intuniv

Product / population
Guanfacine extended-release; do not transfer to immediate-release tablets.
Renal measure
Qualitative significant renal impairment; no numeric reduction specified.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

A dose reduction may be necessary with significant renal impairment. The source does not specify a fixed renal dose-reduction percentage. Pediatric renal pharmacokinetics have not been assessed. Adult renal clearance falls with declining kidney function; dialysis contributes only about 15% of total clearance. That clearance figure is not a supplemental-dose instruction.

Source revision: Revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/intuniv-drug/

Scope: Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Source-first renal review

Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - Intuniv

Qualitative renal precaution. No complete numerical renal schedule is supplied by this selected finding.

Guanfacine extended-release; do not transfer to immediate-release tablets.

Renal method: Qualitative significant renal impairment; no numeric reduction specified.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - Intuniv
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/intuniv-drug/

Product and population scope

Guanfacine extended-release; do not transfer to immediate-release tablets.

RDM33-SCOPE-guanfacine-intuniv-er-C1 · Source section: Exact product identity and selected populationRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Intuniv

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GlobalRPh-hosted RX List · Guanfacine extended-release; do not transfer to immediate-release tablets.

Renal method: Qualitative significant renal impairment; no numeric reduction specified.
Source date: Revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Qualitative renal precaution. No complete numerical renal schedule is supplied by this selected finding.

Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

A dose reduction may be necessary with significant renal impairment. The source does not specify a fixed renal dose-reduction percentage. Pediatric renal pharmacokinetics have not been assessed. Adult renal clearance falls with declining kidney function; dialysis contributes only about 15% of total clearance. That clearance figure is not a supplemental-dose instruction.

RDM33-rxlist-guanfacine-intuniv-er-C1 · Source locator: Use in specific populations: renal impairment; clinical pharmacology: renal impairment.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/intuniv-drug/
Retrieved
2026-09-07
Renal-function method
Qualitative significant renal impairment; no numeric reduction specified.
Source date/version
Revision date not established in selected retrieval.
Hash meaning
SHA-256 of the local authored summary only; original HTML/PDF/SPL bytes are not bundled or hashed.
Local summary SHA-256
438cf5ae0bbc8d2ee09e7f422d63bea2d7b6d9eb0f21cdd04a7dbc55d736ca09

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/intuniv-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
35c5958cec1a0aa4a72407716e3c8c07589536689b9d0d6c19b946102368fb69
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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