GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Glasdegib tablets (DAURISMO)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Glasdegib (Daurismo)

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Rxlist source

GlobalRPh RX List - Glasdegib (Daurismo)

Product / population
DAURISMO oral oncology product; regimen and concomitant therapy require oncology review.
Renal measure
eGFR (mL/min as printed); severe impairment and QTc risk.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

No dose modification is specified for eGFR 15-89. Severe impairment, eGFR 15-29, increases exposure and requires increased monitoring for adverse reactions, including QTc prolongation. Pharmacokinetics in end-stage disease requiring hemodialysis have not been studied. Monitor kidney function and electrolytes with the label's baseline and follow-up safety plan. A no-modification statement for the studied range does not establish an ESRD regimen or eliminate electrocardiographic monitoring.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/daurismo-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - Glasdegib (Daurismo)

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

DAURISMO oral oncology product; regimen and concomitant therapy require oncology review.

Renal method: eGFR (mL/min as printed); severe impairment and QTc risk.
Retrieved: 2026-09-07

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Original content / product scopeGlobalRPh RX List - Glasdegib (Daurismo)
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/daurismo-drug/

Exact product and population

DAURISMO oral oncology product; regimen and concomitant therapy require oncology review.

RDM39-SCOPE-glasdegib-daurismo · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Glasdegib (Daurismo)

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GlobalRPh-hosted RX List · DAURISMO oral oncology product; regimen and concomitant therapy require oncology review.

Renal method: eGFR (mL/min as printed); severe impairment and QTc risk.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

No dose modification is specified for eGFR 15-89. Severe impairment, eGFR 15-29, increases exposure and requires increased monitoring for adverse reactions, including QTc prolongation. Pharmacokinetics in end-stage disease requiring hemodialysis have not been studied. Monitor kidney function and electrolytes with the label's baseline and follow-up safety plan. A no-modification statement for the studied range does not establish an ESRD regimen or eliminate electrocardiographic monitoring.

RDM39-rxlist-glasdegib-daurismo-12a6348d47-C1 · Source locator: Selected renal dosing, use in renal impairment, warnings and clinical pharmacology subsections; see named sections in summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/daurismo-drug/
Retrieved
2026-09-07
Renal-function method
eGFR (mL/min as printed); severe impairment and QTc risk.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
9a57959bac207c818bb647ad097955aa7a4c653fc6cbb40993051ec1cf5119fb

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/daurismo-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
c2b7140a6bcfddf27e90c90ff288ad95867633e647264ca14c10a1aad2b77fdd
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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