Original GlobalRPh source
- Product / population
- Preserved GlobalRPh source, not a freshly verified product label
- Renal measure
- Use the method specified in the original source
Historical source: not automatically current. Review current official labeling and separately attributed additions before use.
GlobalRPh general renal statement
Renal Impairment: Clearance of quinine is decreased in patients with severe chronic renal failure. The dosage and dosing frequency should be reduced. In patients with acute uncomplicated malaria and severe chronic renal impairment, the following dosage regimen is recommended: one loading dose of 648 mg QUALAQUIN followed 12 hours later by maintenance doses of 324 mg every 12 hours.
The effects of mild and moderate renal impairment on the safety and pharmacokinetics of quinine sulfate are not known.
Source: https://globalrph.com/renal/medications-with-general-renal-dosing-statements/