GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Methotrexate tablets/injection

GlobalRPh general statementBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons
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GlobalRPh general renal statement

Warnings: Methotrexate elimination is reduced in patients with impaired renal function, ascities, or pleural effusions. Such patients require especially careful monitoring for toxicity, and require dose reduction or, in some cases, discontinuation of methotrexate administration.

Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://globalrph.com/renal/medications-with-general-renal-dosing-statements/

Scope: Preserved historical source; no fresh clinical approval GlobalRPh v6.6.

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Retrieved: 2026-09-05

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Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/medications-with-general-renal-dosing-statements/

GlobalRPh general renal statement

Warnings: Methotrexate elimination is reduced in patients with impaired renal function, ascities, or pleural effusions. Such patients require especially careful monitoring for toxicity, and require dose reduction or, in some cases, discontinuation of methotrexate administration.

GRPH-general-methotrexate-01 · Source section: GlobalRPh general renal statementRenal section finder

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/medications-with-general-renal-dosing-statements/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph general · Numbered general entry 13
Local text SHA-256
e52e2e9387287cd3b5d93a957227ea51a511d20b2791b15647875a75dba16f66
Import versus clinical validation
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The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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