GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Gadoversetamide injection (OPTIMARK)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Gadoversetamide (OptiMARK)

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Rxlist source

GlobalRPh RX List - Gadoversetamide (OptiMARK)

Product / population
Intravenous OPTIMARK; historical-source restrictions retained, current availability not established.
Renal measure
Indexed GFR (mL/min/1.73 m2) and acute kidney injury.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

Do not administer OPTIMARK in acute kidney injury or chronic severe kidney disease with GFR below 30. The source identifies NSF and renal adverse-effect concerns and advises screening before use. Renal dose adjustment has not been studied. Hemodialysis removal does not supersede the contraindication or establish protection from NSF. Preserve the specific product restriction rather than applying a newer, lower-risk agent's recommendations to OPTIMARK.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/optimark-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - Gadoversetamide (OptiMARK)

Historical product / current restriction. Historical renal instructions do not establish current prescribing eligibility. Read the regulatory caution.

Intravenous OPTIMARK; historical-source restrictions retained, current availability not established.

Renal method: Indexed GFR (mL/min/1.73 m2) and acute kidney injury.
Retrieved: 2026-09-07

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Original content / product scopeGlobalRPh RX List - Gadoversetamide (OptiMARK)
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/optimark-drug/

Exact product and population

Intravenous OPTIMARK; historical-source restrictions retained, current availability not established.

RDM39-SCOPE-gadoversetamide-optimark · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Gadoversetamide (OptiMARK)

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GlobalRPh-hosted RX List · Intravenous OPTIMARK; historical-source restrictions retained, current availability not established.

Renal method: Indexed GFR (mL/min/1.73 m2) and acute kidney injury.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Historical product / current restriction. Historical renal instructions do not establish current prescribing eligibility. Read the regulatory caution.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

Do not administer OPTIMARK in acute kidney injury or chronic severe kidney disease with GFR below 30. The source identifies NSF and renal adverse-effect concerns and advises screening before use. Renal dose adjustment has not been studied. Hemodialysis removal does not supersede the contraindication or establish protection from NSF. Preserve the specific product restriction rather than applying a newer, lower-risk agent's recommendations to OPTIMARK.

RDM39-rxlist-gadoversetamide-optimark-c12a74140d-C1 · Source locator: Selected renal dosing, use in renal impairment, warnings and clinical pharmacology subsections; see named sections in summary.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/optimark-drug/
Retrieved
2026-09-07
Renal-function method
Indexed GFR (mL/min/1.73 m2) and acute kidney injury.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
08a39c9d6ad30c814619a2da94ac2a99f8c13e9629cb8e70aaa4ef85426cb0ec

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/optimark-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
afc0fe0b278253de36adb8d04f115d984dd3f4af8c08684aef68845771f2f094
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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