GlobalRPh RX List - LYTGOBI
- Product / population
- LYTGOBI oral tablets; selected renal pharmacokinetics, not a full oncology protocol.
- Renal measure
- Cockcroft-Gault creatinine clearance (CrCl), mL/min; not indexed laboratory eGFR.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No clinically meaningful exposure difference was identified with CrCl 30 to 89. Severe impairment, CrCl 15 to 29, and end-stage disease requiring dialysis were not studied. This is pharmacokinetic evidence, not a dose schedule for unstudied groups.