GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Fitusiran injection (QFITLIA)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

QFITLIA

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Rxlist source

GlobalRPh RX List - QFITLIA

Product / population
Subcutaneous fitusiran; selected renal evidence limits for the hemophilia product, not its antithrombin-based dose algorithm.
Renal measure
Indexed eGFR, mL/min/1.73 m2.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

No dedicated study of renal impairment was conducted. Population pharmacokinetics found no exposure effect in mild impairment, defined as eGFR 60 to below 90 mL/min/1.73 m2. The pivotal studies included only one participant in the moderate category, eGFR 30 to below 60. These data do not establish a moderate/severe-impairment or dialysis dose. Use the product-specific antithrombin-guided hematology protocol; no renal dose has been calculated from the limited exposure data.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/qfitlia-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Source-first renal review

Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - QFITLIA

Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.

Subcutaneous fitusiran; selected renal evidence limits for the hemophilia product, not its antithrombin-based dose algorithm.

Renal method: Indexed eGFR, mL/min/1.73 m2.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - QFITLIA
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/qfitlia-drug/

Exact product and population

Subcutaneous fitusiran; selected renal evidence limits for the hemophilia product, not its antithrombin-based dose algorithm.

RDM35-SCOPE-fitusiran-qfitlia · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - QFITLIA

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GlobalRPh-hosted RX List · Subcutaneous fitusiran; selected renal evidence limits for the hemophilia product, not its antithrombin-based dose algorithm.

Renal method: Indexed eGFR, mL/min/1.73 m2.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

No dedicated study of renal impairment was conducted. Population pharmacokinetics found no exposure effect in mild impairment, defined as eGFR 60 to below 90 mL/min/1.73 m2. The pivotal studies included only one participant in the moderate category, eGFR 30 to below 60. These data do not establish a moderate/severe-impairment or dialysis dose. Use the product-specific antithrombin-guided hematology protocol; no renal dose has been calculated from the limited exposure data.

RDM35-rxlist-fitusiran-qfitlia-158e93ad85-C1 · Source locator: Clinical Pharmacology: Specific Populations.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/qfitlia-drug/
Retrieved
2026-09-07
Renal-function method
Indexed eGFR, mL/min/1.73 m2.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
a8bde314a304e77e0161d2a220e0f746fcb291841fe109bacf714a1f35cbc3a9

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/qfitlia-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
bb28a379e4968ac162523e9931bb60105c2ad0bcd8ecef151c57d9cfaee34df8
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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