GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Fexofenadine (Allegra)

GlobalRPh source pageBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons
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Usual Dosing (Adults)

Seasonal allergic rhinitis and chronic idiopathic urticaria: adults/children >=12 years, tablets 60 mg twice daily or 180 mg daily with water. Start 60 mg daily with reduced renal function. Children 6 to 11: tablets 30 mg twice daily with water; renal starting dose 30 mg daily.

ALLEGRA ODT for ages 6 to 11 only: 30 mg twice daily, renal starting dose 30 mg daily. Disintegrate on tongue and swallow with or without water, on an empty stomach. Do not chew or remove from original blister until administration.

Oral suspension for seasonal allergic rhinitis, ages 2 to 11: 30 mg twice daily; renal starting dose 30 mg (5 mL) daily.

Suspension for chronic idiopathic urticaria: ages 2 to 11, 30 mg (5 mL) twice daily; ages 6 months to <2 years, 15 mg (2.5 mL) twice daily. With reduced renal function, start corresponding doses once daily. Shake well before each use.

Renal Dosing

CrCl 41 to 80 and 11 to 40 mL/min: peak concentrations 87% and 111% higher, half-lives 59% and 72% longer, respectively, versus healthy subjects. Dialysis subjects (CrCl <=10): peak concentration 82% higher and half-life 31% longer. Based on increased availability/half-life, start adults at 60 mg daily; ages 2 to 11 at 30 mg daily; ages 6 months to <2 years at 15 mg daily.

Hemodialysis

Insufficient data.

Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://globalrph.com/renal/fexofenadine/

Scope: Preserved historical source; no fresh clinical approval GlobalRPh v6.6.

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Retrieved: 2026-09-05

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Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/fexofenadine/

Usual Dosing (Adults)

Seasonal allergic rhinitis and chronic idiopathic urticaria: adults/children >=12 years, tablets 60 mg twice daily or 180 mg daily with water. Start 60 mg daily with reduced renal function. Children 6 to 11: tablets 30 mg twice daily with water; renal starting dose 30 mg daily.

ALLEGRA ODT for ages 6 to 11 only: 30 mg twice daily, renal starting dose 30 mg daily. Disintegrate on tongue and swallow with or without water, on an empty stomach. Do not chew or remove from original blister until administration.

Oral suspension for seasonal allergic rhinitis, ages 2 to 11: 30 mg twice daily; renal starting dose 30 mg (5 mL) daily.

Suspension for chronic idiopathic urticaria: ages 2 to 11, 30 mg (5 mL) twice daily; ages 6 months to <2 years, 15 mg (2.5 mL) twice daily. With reduced renal function, start corresponding doses once daily. Shake well before each use.

GRPH-fexofenadine-01 · Source section: Usual Dosing (Adults)Renal section finder

Renal Dosing

CrCl 41 to 80 and 11 to 40 mL/min: peak concentrations 87% and 111% higher, half-lives 59% and 72% longer, respectively, versus healthy subjects. Dialysis subjects (CrCl <=10): peak concentration 82% higher and half-life 31% longer. Based on increased availability/half-life, start adults at 60 mg daily; ages 2 to 11 at 30 mg daily; ages 6 months to <2 years at 15 mg daily.

GRPH-fexofenadine-02 · Source section: Renal DosingRenal section finder

Hemodialysis

Insufficient data.

GRPH-fexofenadine-03 · Source section: HemodialysisRenal section finder

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/fexofenadine/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
c0630324aa58fd43f8530bb4f5261a7d3333170e42465774408634af2929616d
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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