GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Ezetimibe - single agent

Local official-label summaryBase record retrieved 2026-09-05See the evidence for this drug2 sources available - open source summaries, references and comparisons
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Official source

Ezetimibe single-agent tablets - renal dosing

Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal measure
No renal-function dose bands specified for this summary.

Dosing / renal protocol and limits

Adult single-agent ezetimibe: 10 mg orally once daily, with or without food. Renal impairment does not require adjustment. Give at least 2 hours before or 4 hours after a bile-acid sequestrant. Do not apply this single-agent renal statement to a fixed combination without checking the other component's dosing restrictions. The source also identifies cyclosporine-related exposure changes and myopathy precautions.

Source revision: DailyMed updated 2024-03-05. | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b3842f6-c80a-47b8-8a82-b69e465b05f7

Scope: Locally included source-specific summary. Regimen differences are not automatically resolved. GlobalRPh v6.6.

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Evidence sources and renal implications

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Official product label

Ezetimibe single-agent tablets - renal dosing

Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Retrieved: 2026-09-05

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Handbook

Renal Drug Handbook, 5th edition - Ezetimibe

Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Renal method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Retrieved: 2026-09-05

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Renal dosing and precautions

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Handbook source

Renal Drug Handbook, 5th edition - Ezetimibe

Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.

Historical renal / replacement-therapy guidanceRead this complete source summary

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Original content / product scopeEzetimibe single-agent tablets - renal dosingRenal Drug Handbook, 5th edition - Ezetimibe
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Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b3842f6-c80a-47b8-8a82-b69e465b05f7

Product and population scope

Adult Ezetimibe - single agent. Use only the product, route, indication and renal-replacement setting explicitly stated in the source protocol selected below. Sources are alternatives to compare, not ingredients of a blended regimen.

SCOPE-ezetimibe · Source section: Editorial scope; each clinical recommendation is separately attributed belowRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Ezetimibe single-agent tablets - renal dosing

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NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Source date: DailyMed updated 2024-03-05.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Adult single-agent ezetimibe: 10 mg orally once daily, with or without food. Renal impairment does not require adjustment. Give at least 2 hours before or 4 hours after a bile-acid sequestrant. Do not apply this single-agent renal statement to a fixed combination without checking the other component's dosing restrictions. The source also identifies cyclosporine-related exposure changes and myopathy precautions.

RDM30-083-ezetimibe-1 · Source locator: Ezetimibe single-agent tablets - renal dosing; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b3842f6-c80a-47b8-8a82-b69e465b05f7
Retrieved
2026-09-05
DailyMed Set ID
5b3842f6-c80a-47b8-8a82-b69e465b05f7
Renal-function method
No renal-function dose bands specified for this summary.
Source date/version
DailyMed updated 2024-03-05.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
7a014ad8ff6b12604fd0cf8327bb76dc43262c2b2ecbd98e17b0382558883ad2
Separate handbook layer

Renal Drug Handbook cross-check

Handbook

Renal Drug Handbook, 5th edition - Ezetimibe

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UK Renal Pharmacy Group / CRC Press · Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Renal method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Source date: 5th edition; 2019 copyright; historical reference
Retrieved: 2026-09-05

Historical handbook cross-check; not a current U.S. protocol

Historical renal / replacement-therapy guidance

The 20-50, 10-20 and <10 mL/min bands retain the usual indication-specific dose. The listed dose is 10 mg orally daily. Dialytic removal is considered unlikely in PD, HD, high-flux and continuous therapy; usual dosing is retained. This applies to ezetimibe itself, not a fixed statin combination.

HB30-ezetimibe-1 · Source locator: Printed page 410: renal impairment, RRT and other information

Source-specific limits

Separate source recommendation, not proof of agreement or contemporary clinical validation. Dialysis predictions are retained with their original certainty.

Source identity and provenance
Retrieved
2026-09-05
Handbook page
5th edition, printed p. 410; uploaded PDF p. 429
Renal-function method
Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Source date/version
5th edition; 2019 copyright; historical reference
U.S. product identity basis
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b3842f6-c80a-47b8-8a82-b69e465b05f7
Hash meaning
Local paraphrase; original book not redistributed
Local summary SHA-256
67076cd5093c652a3fe39d4212d31fbab96a9a7efda89df8c9cdfe3450cca947

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 0 RX List, 0 professional, 1 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b3842f6-c80a-47b8-8a82-b69e465b05f7
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
fbe0b5c5e21917cf7cf5cbb4f08ce1ab3c365a0154fb8b66e3fa3571af3a43a1
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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