GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Everolimus transplant tablets (ZORTRESS)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

ZORTRESS

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Rxlist source

GlobalRPh RX List - ZORTRESS

Product / population
ZORTRESS transplant formulation and combination context; not AFINITOR oncology guidance.
Renal measure
Qualitative renal impairment; exposure-guided transplant combination monitoring.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The source does not require adjustment for renal impairment alone. That does not remove nephrotoxicity from the transplant combination: reduced cyclosporine exposure is required with everolimus, and the label uses everolimus trough monitoring with a 3-8 ng/mL target. Those co-therapy and monitoring instructions belong to the transplant regimen; do not transfer them to oncology AFINITOR or use a renal no-adjustment statement to leave cyclosporine unreviewed.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/zortress-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - ZORTRESS

No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

ZORTRESS transplant formulation and combination context; not AFINITOR oncology guidance.

Renal method: Qualitative renal impairment; exposure-guided transplant combination monitoring.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - ZORTRESS
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/zortress-drug/

Exact product and population

ZORTRESS transplant formulation and combination context; not AFINITOR oncology guidance.

RDM37-SCOPE-everolimus-zortress · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - ZORTRESS

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GlobalRPh-hosted RX List · ZORTRESS transplant formulation and combination context; not AFINITOR oncology guidance.

Renal method: Qualitative renal impairment; exposure-guided transplant combination monitoring.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The source does not require adjustment for renal impairment alone. That does not remove nephrotoxicity from the transplant combination: reduced cyclosporine exposure is required with everolimus, and the label uses everolimus trough monitoring with a 3-8 ng/mL target. Those co-therapy and monitoring instructions belong to the transplant regimen; do not transfer them to oncology AFINITOR or use a renal no-adjustment statement to leave cyclosporine unreviewed.

RDM37-rxlist-everolimus-zortress-5e97f997c5-C1 · Source locator: Renal Impairment; reduced cyclosporine exposure and therapeutic monitoring.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/zortress-drug/
Retrieved
2026-09-07
Renal-function method
Qualitative renal impairment; exposure-guided transplant combination monitoring.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
910ab741dd71f022771c68c99a8177ccccea2b65fa47e62f21c142e397c8fc37

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/zortress-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
67202ba432744fa53b90cc99042773b25903ffd03857898465731691499050e9
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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