VELSIPITY: selected primary-label renal guidance and limits
What matters first
Product: Adult oral VELSIPITY for labeled ulcerative colitis; renal PK finding only, not a complete prescribing checklist.
- Renal action / finding
- Severe-renal PK finding; no dose algorithm derived.
- Evidence or dialysis limit
- Selected passage does not establish dialysis dosing.
- Monitoring / application
- Apply the full pretreatment and safety checklist, not this PK finding alone.
- Product / population
- Adult oral VELSIPITY for labeled ulcerative colitis; renal PK finding only, not a complete prescribing checklist.
- Renal measure
- eGFR <=29 mL/min as printed in selected PK text; indexing not specified there
- Source revision
- Revision date not captured in selected review; retrieval date is not revision date.
- Retrieved
- 2026-11-07 (not the revision date)
Selected passage does not establish dialysis dosing.
Selected renal section, not a complete prescribing monograph. A label and its mirror are not independent evidence.
Section 12.3, Specific Populations
No clinically significant pharmacokinetic difference was observed in severe renal impairment (eGFR <=29 mL/min, source wording). This is a PK observation, not a new renal-dose algorithm. The selected text does not establish dialysis dosing. Full cardiac, infection, ophthalmic and other pretreatment requirements remain separate.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=65171e4a-d136-4abc-b08c-c40c1b486ff6
