GlobalRPh RX List - PARSABIV
- Product / population
- Adults with secondary hyperparathyroidism and CKD on hemodialysis; not nondialysis CKD.
- Renal measure
- Hemodialysis schedule, corrected calcium and PTH; not an eGFR dose-band algorithm.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Ensure corrected calcium is at least the lower limit of normal before initiation, dose increase or restart. The initial dose is 5 mg IV three times weekly, only at the end of hemodialysis. Individualized maintenance ranges from 2.5 to 15 mg three times weekly. Do not give catch-up doses for missed dialysis; resume after the next session. After >2 weeks of missed doses, restart 5 mg, or 2.5 mg if that was the last dose. Check corrected calcium 1 week after initiation/adjustment and every 4 weeks during maintenance; check PTH after 4 weeks. This selected card is not the complete hypocalcemia/titration protocol.