GlobalRPh Renal Dosing Masterv7.4
Renal Dosing Master: fast drug lookup
Product-specific reference

Escitalopram tablets (adults)

Read renal action and limits

Lexapro / Escitalopram

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)

Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist

Choose a source to read (4)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

1 additional source qualifications - review before use
Lexapro - product and source limitations

Use caution in severe impairment. The absence of a studied regimen is not evidence for a dialysis dose.

Before applying: Apply only to the stated formulation, indication and renal population.

Also check: Lexapro - product and source limitations

Handbook source

Renal Drug Handbook, fifth edition - Escitalopram tablets (adults)

Product / population
Historical renal/RRT cross-check for the named ingredient; not a current U.S. prescribing instruction.
Renal measure
Book table headings say GFR (mL/min); the preface states adjustment information is based on Cockcroft-Gault CrCl, not indexed eGFR. Do not substitute methods.
Source revision
Fifth edition, 2019
Retrieved
2026-09-05 (not the revision date)

This is historical cautious-use advice where the label does not establish a dose below CrCl 20. The printed book bands overlap at 30; they are not an automated algorithm.

Historical renal and dialysis observations

The book retains usual dosing at 30-50 mL/min; at 10-30 and below 10, it favors low initiation and slow titration. HD/high-flux removal is described as absent, and peritoneal/continuous removal as unlikely.

Source revision: Fifth edition, 2019 | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source:

Scope: Historical source, separately displayed. Renal tables were read with page-image inspection. GlobalRPh v7.4.

Full source card / provenance

All sources, comparison tools and evidence navigation
Added / rechecked in v7.4

Read source findings

Read source-specific summaries and their qualifications. Retrieval date is not label revision date. Recent review does not imply clinical approval.

Official

Lexapro - labeled renal guidance

Retrieved: 2026-11-07
Source revision: DailyMed SPL version 45, posted Jan 01, 2026

Renal measure: Creatinine clearance (CrCl), mL/min

Read this dated source finding
Rxlist

Lexapro - selected RX renal passage

Retrieved: 2026-11-07
Source revision: Mirror revision not established in the reviewed passage.

Renal measure: Use the renal measure explicitly present in the RX passage.

Read this dated source finding
See all retained evidence sources
Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

Official product label

Escitalopram tablets (adults) - selected U.S. labeling

Adult major depressive disorder and generalized anxiety disorder; oral escitalopram tablets. Pediatric and oral-solution dosing are outside this summary.

Renal method: CrCl in mL/min for the below-20 data boundary; no severe-renal dose algorithm.
Retrieved: 2026-09-05

Handbook

Renal Drug Handbook, fifth edition - Escitalopram tablets (adults)

Historical renal/RRT cross-check for the named ingredient; not a current U.S. prescribing instruction.

Renal method: Book table headings say GFR (mL/min); the preface states adjustment information is based on Cockcroft-Gault CrCl, not indexed eGFR. Do not substitute methods.
Retrieved: 2026-09-05

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-specific review points

Read the attributed comparison notes and source cards below. No conflict has been silently adjudicated.

Source-quality holds
Find text within this drug
Find a term without leaving this drug

Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

Find:

Enter at least two characters. This in-page search is processed in your browser. Do not enter patient identifiers; advertising scripts also run on this page.

All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

Open / share selected sources

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Source scope / renal recommendation differences

Lexapro - product and source limitations

Use caution in severe impairment. The absence of a studied regimen is not evidence for a dialysis dose.

How to use this: Apply only to the stated formulation, indication and renal population.

Selected renal passages reviewed; independent clinician adjudication pending.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
Official source

Escitalopram tablets (adults) - selected U.S. labeling

Adult major depressive disorder and generalized anxiety disorder; oral escitalopram tablets. Pediatric and oral-solution dosing are outside this summary.

Method: CrCl in mL/min for the below-20 data boundary; no severe-renal dose algorithm.

Handbook source

Renal Drug Handbook, fifth edition - Escitalopram tablets (adults)

Historical renal/RRT cross-check for the named ingredient; not a current U.S. prescribing instruction.

Method: Book table headings say GFR (mL/min); the preface states adjustment information is based on Cockcroft-Gault CrCl, not indexed eGFR. Do not substitute methods.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c68f89b-1d34-4735-9631-817f012935d7

Product and population scope

Adult major depressive disorder and generalized anxiety disorder; oral escitalopram tablets. Pediatric and oral-solution dosing are outside this summary.

RDM31-escitalopram-tablets-scope · Source section: Editorial scope tied to selected U.S. labelRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Escitalopram tablets (adults) - selected U.S. labeling

Open original reference

Open / share this exact local source

U.S. product labeling / DailyMed · Adult major depressive disorder and generalized anxiety disorder; oral escitalopram tablets. Pediatric and oral-solution dosing are outside this summary.

Renal method: CrCl in mL/min for the below-20 data boundary; no severe-renal dose algorithm.
Source date: Label revision date not separately recorded; retrieval date is not the revision date.
Retrieved: 2026-09-05

Selected dosing/renal sections read; concise local summary, not full prescribing information.

Labeled basic dosing

The adult starting/recommended dose is 10 mg orally once daily. Based on response and tolerability, increase no sooner than one week to a maximum 20 mg/day. Most older adults and patients with hepatic impairment use 10 mg/day.

RDM31-escitalopram-tablets-label-dose · Source locator: 2.1, 2.2, 2.5

Renal information and dialysis

No change is needed for mild or moderate renal impairment. At adult CrCl below 20 mL/min, a recommended dosage has not been determined. A dialysis-specific regimen is not supplied.

RDM31-escitalopram-tablets-label-renal · Source locator: 2.5; 8.7

Selected warnings and limits

Monitor clinical worsening or suicidality, serotonin syndrome and hyponatremia; screen for bipolar disorder and review interacting medicines.

RDM31-escitalopram-tablets-label-limits · Source locator: Boxed warning; 2.4; 5

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c68f89b-1d34-4735-9631-817f012935d7
Retrieved
2026-09-05
DailyMed Set ID
9c68f89b-1d34-4735-9631-817f012935d7
Renal-function method
CrCl in mL/min for the below-20 data boundary; no severe-renal dose algorithm.
Source date/version
Label revision date not separately recorded; retrieval date is not the revision date.
Hash meaning
SHA-256 identifies this local summary, not original SPL XML or label PDF.
Local summary SHA-256
7d6ce892c9086cdb4520017d8fae78115c6c5e5276152162e6a4c6913ec0ebf9
Official

Lexapro - labeled renal guidance

Open original reference

Open / share this exact local source

DailyMed / product prescribing information · Escitalopram (Lexapro), oral tablet

Renal method: Creatinine clearance (CrCl), mL/min
Source date: DailyMed SPL version 45, posted Jan 01, 2026
Retrieved: 2026-11-07

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

Renal guidance: 8.7 Renal Impairment

Mild or moderate impairment does not require adjustment. An adult dose has not been established for CrCl below 20 mL/min. Use caution in severe impairment. The absence of a studied regimen is not evidence for a dialysis dose.

RDM74-lexapro-official-1 · Source locator: Renal guidance: 8.7 Renal Impairment

Source identity and provenance
Source family
product_label
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=13bb8267-1cab-43e5-acae-55a4d957630a
Retrieved
2026-11-07
Renal-function method
Creatinine clearance (CrCl), mL/min
Source date/version
DailyMed SPL version 45, posted Jan 01, 2026
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
9d44c9c468fff4ed2c19eb18f6fbeb6c43cd2a6274ae5b1f7ac5d8d7388f795a
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

Lexapro - selected RX renal passage

Open original reference

Open / share this exact local source

GlobalRPh RX List / product-label mirror · Escitalopram (Lexapro), oral tablet

Renal method: Use the renal measure explicitly present in the RX passage.
Source date: Mirror revision not established in the reviewed passage.
Retrieved: 2026-11-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected renal passages reviewed; independent clinician adjudication pending.

RX List: selected renal passage

Mild or moderate impairment does not require adjustment. An adult dose has not been established for CrCl below 20 mL/min.

RDM74-lexapro-rxlist-1 · Source locator: RX List: selected renal passage

Source-specific limits

This mirror and the underlying product label share a source family.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/lexapro-drug/
Retrieved
2026-11-07
Renal-function method
Use the renal measure explicitly present in the RX passage.
Source date/version
Mirror revision not established in the reviewed passage.
Hash meaning
SHA-256 of the local selected-source summary
Local summary SHA-256
de40043a7e1d56a24e5db6e273cf4334a39d00845824be813c61a9e3492eba89
Separate handbook layer

Renal Drug Handbook cross-check

Handbook

Renal Drug Handbook, fifth edition - Escitalopram tablets (adults)

Open / share this exact local source

UK Renal Pharmacy Group / CRC Press · Historical renal/RRT cross-check for the named ingredient; not a current U.S. prescribing instruction.

Renal method: Book table headings say GFR (mL/min); the preface states adjustment information is based on Cockcroft-Gault CrCl, not indexed eGFR. Do not substitute methods.
Source date: Fifth edition, 2019
Retrieved: 2026-09-05

Historical source, separately displayed. Renal tables were read with page-image inspection.

Historical renal and dialysis observations

The book retains usual dosing at 30-50 mL/min; at 10-30 and below 10, it favors low initiation and slow titration. HD/high-flux removal is described as absent, and peritoneal/continuous removal as unlikely.

RDM31-escitalopram-tablets-book · Source locator: Dose in renal impairment; renal replacement therapies; Other information

Source-specific limits

This is historical cautious-use advice where the label does not establish a dose below CrCl 20. The printed book bands overlap at 30; they are not an automated algorithm.

Source identity and provenance
Retrieved
2026-09-05
Handbook page
Printed page(s) 386-387; PDF page(s) 405,406
Renal-function method
Book table headings say GFR (mL/min); the preface states adjustment information is based on Cockcroft-Gault CrCl, not indexed eGFR. Do not substitute methods.
Source date/version
Fifth edition, 2019
U.S. product identity basis
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c68f89b-1d34-4735-9631-817f012935d7
Hash meaning
SHA-256 identifies the local paraphrase; the source PDF is not redistributed.
Local summary SHA-256
eb79c1e11a7a59948bbcf943c8983e325e7e56a69daecf749b605684bf6cf7df

Provenance and preservation

Additional summaries stored on this page: 2 official-label, 1 RX List, 0 professional, 1 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c68f89b-1d34-4735-9631-817f012935d7
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
11c82519c49aba357768684539899c3ca1d0b8835559225b335bf5cc53c3cb37
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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