Lovenox - labeled renal guidance
Renal action and limits
Enoxaparin sodium (Lovenox), adult subcutaneous prophylaxis and DVT treatment
Creatinine clearance (CrCl), mL/min
- Action or finding
- For adult CrCl below 30 mL/min, labeled abdominal surgery, hip/knee replacement, and acutely ill medical prophylaxis use 30 mg SC daily. Labeled DVT treatment with warfarin uses 1 mg/kg SC daily.
- Limits and monitoring
- ACS and STEMI have indication- and age-specific instructions. Assess bleeding and neuraxial procedure timing separately.
- Before use
- Apply only to the stated formulation, indication and renal population.
- Product / population
- Enoxaparin sodium (Lovenox), adult subcutaneous prophylaxis and DVT treatment
- Renal measure
- Creatinine clearance (CrCl), mL/min
- Source revision
- DailyMed SPL version 33, posted May 29, 2026
- Retrieved
- 2026-11-07 (not the revision date)
Renal guidance: 2.3 Dose Reduction for Patients with Severe Renal Impairment / 8.7 Renal Impairment
For adult CrCl below 30 mL/min, labeled abdominal surgery, hip/knee replacement, and acutely ill medical prophylaxis use 30 mg SC daily. Labeled DVT treatment with warfarin uses 1 mg/kg SC daily. ACS and STEMI have indication- and age-specific instructions. Assess bleeding and neuraxial procedure timing separately.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5017a927-2a24-4f27-89f9-27c805bf7d59
