Sustiva
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Adults: 600 mg orally daily, fasting, preferably at bedtime; renal dose modification is not required.
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Preserved historical content; not revalidated as current prescribing guidance.
Adults with HIV; product-specific renal recommendations.
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Adults with HIV; product-specific renal recommendations.
Preserved source. Not revalidated as current labeling.
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The interacting-drug recommendations are preserved from the historical page and require comparison with current HIV guidance.
Adults: SUSTIVA 600 mg orally once daily with a protease inhibitor and/or NRTIs. Take on an empty stomach, preferably at bedtime. Food increases concentrations and may increase adverse reactions; bedtime dosing can improve nervous-system tolerability. Always combine with other antiretrovirals.
With voriconazole: increase voriconazole maintenance to 400 mg every 12 hours and decrease efavirenz to 300 mg daily using capsules (one 200 mg plus two 50 mg, or six 50 mg capsules). Do not break SUSTIVA tablets.
With rifampin in patients >=50 kg, the source recommends increasing efavirenz to 800 mg daily.
No adjustments needed.
Insufficient data.
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Adults: 600 mg orally daily, fasting, preferably at bedtime; renal dose modification is not required.
efavirenz:nih-arv-efavirenz-1 · Source locator: Appendix B: Efavirenz row
The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.
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