Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist
Choose a source to read (3)
Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.
1 additional source qualifications - review before use
Preserved GlobalRPh source, not a freshly verified product label
Renal measure
Use the method specified in the original source
Source revision
Historical source; revision not established here
Retrieved
2026-09-05 (not the revision date)
Historical source: not automatically current. Review current official labeling and separately attributed additions before use.
The original page lists controlled-release usual doses but does not explicitly identify a controlled-release renal algorithm. Do not transfer immediate-release interval recommendations to controlled-release products.
Usual Dosing (Adults)
Weight <50 kg: 100 mg every 6 hours or controlled-release 200 mg every 12 hours. Weight >50 kg: 150 mg every 6 hours or controlled-release 300 mg every 12 hours. With no response, may increase to 200 mg every 6 hours. The source maximum required for severe refractory ventricular tachycardia is 400 mg every 6 hours.
Renal Dosing
CrCl >40 mL/min: no change; 30 to 40: 100 mg every 8 hours; 15 to 30: 100 mg every 12 hours; <15: 100 mg every 24 hours.
Alternative source strategy: CrCl 30 to 40, reduce dose 50%; CrCl 15 to 30, reduce dose 75%.
Hemodialysis
100 mg every 24 hours. Not dialyzable.
Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.
Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.
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Before applying a renal protocol
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No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.
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Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.
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Source-by-source comparison
These protocols may disagree and may apply to different settings. This view does not reconcile or endorse a patient-specific regimen.
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Renal-context checklist: population, kidney trend and dialysis
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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.
These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
Source scope / renal recommendation differences
Norpace / Norpace CR - product and source limitations
Confirm the release formulation before selecting an interval and monitor conduction and anticholinergic toxicity.
How to use this: Apply only to the stated formulation, indication and renal population.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Important source distinctions
The original page lists controlled-release usual doses but does not explicitly identify a controlled-release renal algorithm. Do not transfer immediate-release interval recommendations to controlled-release products.
Locally stored source content
Original GlobalRPh protocol
Clinical facts and comments transcribed into a structured reading format. Read the original source for its complete context: https://globalrph.com/renal/disopyramide/
Usual Dosing (Adults)
Weight <50 kg: 100 mg every 6 hours or controlled-release 200 mg every 12 hours. Weight >50 kg: 150 mg every 6 hours or controlled-release 300 mg every 12 hours. With no response, may increase to 200 mg every 6 hours. The source maximum required for severe refractory ventricular tachycardia is 400 mg every 6 hours.
GRPH-disopyramide-01 · Source section: Usual Dosing (Adults)Renal section finder
Renal Dosing
CrCl >40 mL/min: no change; 30 to 40: 100 mg every 8 hours; 15 to 30: 100 mg every 12 hours; <15: 100 mg every 24 hours.
Alternative source strategy: CrCl 30 to 40, reduce dose 50%; CrCl 15 to 30, reduce dose 75%.
Avoid the controlled-release Norpace CR formulation at CrCl 40 mL/min or less. Immediate-release disopyramide has separate clearance-based intervals. Confirm the release formulation before selecting an interval and monitor conduction and anticholinergic toxicity.
GlobalRPh RX List / product-label mirror · Disopyramide phosphate (Norpace / Norpace CR), oral capsules; verify release type
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.
