GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Disopyramide

GlobalRPh source pageBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons
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Renal measure
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The original page lists controlled-release usual doses but does not explicitly identify a controlled-release renal algorithm. Do not transfer immediate-release interval recommendations to controlled-release products.

Usual Dosing (Adults)

Weight <50 kg: 100 mg every 6 hours or controlled-release 200 mg every 12 hours. Weight >50 kg: 150 mg every 6 hours or controlled-release 300 mg every 12 hours. With no response, may increase to 200 mg every 6 hours. The source maximum required for severe refractory ventricular tachycardia is 400 mg every 6 hours.

Renal Dosing

CrCl >40 mL/min: no change; 30 to 40: 100 mg every 8 hours; 15 to 30: 100 mg every 12 hours; <15: 100 mg every 24 hours.

Alternative source strategy: CrCl 30 to 40, reduce dose 50%; CrCl 15 to 30, reduce dose 75%.

Hemodialysis

100 mg every 24 hours. Not dialyzable.

Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://globalrph.com/renal/disopyramide/

Scope: Preserved historical source; no fresh clinical approval GlobalRPh v6.6.

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Preserved GlobalRPh source

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Retrieved: 2026-09-05

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Original content / product scope
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

The original page lists controlled-release usual doses but does not explicitly identify a controlled-release renal algorithm. Do not transfer immediate-release interval recommendations to controlled-release products.

Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/disopyramide/

Usual Dosing (Adults)

Weight <50 kg: 100 mg every 6 hours or controlled-release 200 mg every 12 hours. Weight >50 kg: 150 mg every 6 hours or controlled-release 300 mg every 12 hours. With no response, may increase to 200 mg every 6 hours. The source maximum required for severe refractory ventricular tachycardia is 400 mg every 6 hours.

GRPH-disopyramide-01 · Source section: Usual Dosing (Adults)Renal section finder

Renal Dosing

CrCl >40 mL/min: no change; 30 to 40: 100 mg every 8 hours; 15 to 30: 100 mg every 12 hours; <15: 100 mg every 24 hours.

Alternative source strategy: CrCl 30 to 40, reduce dose 50%; CrCl 15 to 30, reduce dose 75%.

GRPH-disopyramide-02 · Source section: Renal DosingRenal section finder

Hemodialysis

100 mg every 24 hours. Not dialyzable.

GRPH-disopyramide-03 · Source section: HemodialysisRenal section finder

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/disopyramide/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
ae985c3c23447fb5f0f04a56590609f26307bf3ce285943067a37b5bd8f8d8f4
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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