Difelikefalin injection (KORSUVA) | GlobalRPh Renal Dosing Master

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1 additional source qualifications - review before use

Dry weight and post-dialyzer timing are part of the regimen

KORSUVA uses target dry body weight and is administered after blood stops passing through the dialyzer. A missed session resumes at the next HD session.

Before applying: Do not use predialysis fluid-loaded weight by default, give before completion of dialysis, or extrapolate to PD/non-HD CKD.

Also check: Dry weight and post-dialyzer timing are part of the regimen

Rxlist source

GlobalRPh RX List - KORSUVA

Product / population: Adults with moderate-to-severe CKD-associated pruritus receiving hemodialysis.
Renal measure: Hemodialysis schedule and target dry body weight, not an eGFR band.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

Give 0.5 mcg/kg IV into the venous dialysis line at the end of each HD session, using target dry body weight. Administer after blood has stopped circulating through the dialyzer; the drug is dialyzable. If HD is missed, resume at the end of the next treatment rather than adding a replacement dose outside that schedule. Do not transfer this regimen to nondialysis CKD or peritoneal dialysis.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/korsuva-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - KORSUVA

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Adults with moderate-to-severe CKD-associated pruritus receiving hemodialysis.

Renal method: Hemodialysis schedule and target dry body weight, not an eGFR band.
Retrieved: 2026-09-07

Read local renal resultOpen original reference

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Jump to renal guidance Read 1 difference / caution notes Clinician guide

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Renal-context checklist: population, kidney trend and dialysis

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Population Kidney-function trend Renal replacement setting

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See source-specific renal methods and the clinical interpretation guide for the supporting context.

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Source differences and product cautions

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dialysis context

Dry weight and post-dialyzer timing are part of the regimen

KORSUVA uses target dry body weight and is administered after blood stops passing through the dialyzer. A missed session resumes at the next HD session.

How to use this: Do not use predialysis fluid-loaded weight by default, give before completion of dialysis, or extrapolate to PD/non-HD CKD.

GlobalRPh RX List - KORSUVA

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

Rxlist source

GlobalRPh RX List - KORSUVA

Adults with moderate-to-severe CKD-associated pruritus receiving hemodialysis.

Method: Hemodialysis schedule and target dry body weight, not an eGFR band.

Renal dosing, restrictions and evidence limits Read this complete source summary

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Original content / product scope GlobalRPh RX List - KORSUVA

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/korsuva-drug/

Exact product and population

Adults with moderate-to-severe CKD-associated pruritus receiving hemodialysis.

RDM42-SCOPE-difelikefalin-korsuva · Source section: Selected source product scopeRenal section finder

Locally imported selected renal sections

GlobalRPh RX List renal information

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GlobalRPh RX List - KORSUVA

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GlobalRPh-hosted RX List · Adults with moderate-to-severe CKD-associated pruritus receiving hemodialysis.

Renal method: Hemodialysis schedule and target dry body weight, not an eGFR band.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM42-rxlist-difelikefalin-korsuva-270f7788f7-C1 · Source locator: Dosage / Renal impairment / relevant warnings

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/korsuva-drug/
Retrieved: 2026-09-07
Renal-function method: Hemodialysis schedule and target dry body weight, not an eGFR band.
Source date/version: Source revision date not established in selected retrieval.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: 5306291411c02db55d56892bbf8f2a3fb83eb7b62fd0ec82223703f3f69d9bef

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/korsuva-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: d1abdff40cc9cb80e4b4fe1f69de416b51510e6cdf3d82e64bbe9d7d9924cec3
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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