Sodium picosulfate / magnesium oxide / citric acid - CLENPIQ oral solution

CrCl below 30 mL/min is a contraindication because of magnesium accumulation. In mild/moderate impairment or with diuretics, ACE inhibitors, ARBs or NSAIDs, renal-injury risk warrants caution; consider baseline and post-colonoscopy electrolytes, creatinine and BUN.

Correct fluid/electrolyte abnormalities beforehand. Maintain appropriate hydration before, during and after preparation, but use caution with fluid replacement in congestive heart failure. Clear liquids should include balanced electrolyte solutions rather than water alone. Significant vomiting or dehydration also warrants consideration of post-procedure laboratory testing.

These instructions do not establish an alternate renal-dose regimen.

The mirror contraindicates use at CrCl below 30 mL/min because magnesium may accumulate. Lesser renal impairment and concomitant medicines affecting kidney function require caution, hydration assessment and consideration of laboratory monitoring. This is a restriction and risk-management paragraph, not a reduced-dose bowel-preparation schedule.

Do not classify a patient above the contraindication threshold as risk-free. Consult the separately dated official source for the checked fluid and electrolyte precautions.