GlobalRPh RX List - JEVTANA
- Product / population
- Adult IV cabazitaxel for the labeled prostate-cancer setting; no-adjustment statement explicitly excludes patients requiring hemodialysis.
- Renal measure
- CLcr; the selected ESRD warning is printed in mL/min/1.73 m2, with other sections using mL/min.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No renal dose adjustment is required for patients who do not need hemodialysis. Monitor patients with end-stage renal disease carefully; the source defines that group using CLcr below 15 mL/min/1.73 m2 and has very limited exposure data. Do not extend the nondialysis statement into a validated hemodialysis regimen. The page mixes indexed and unindexed clearance units across sections, so retain the stated unit and reconcile the method before applying a numeric boundary. Hepatic, marrow and other toxicity modifications remain separate.