GlobalRPh RX List - BRIVIACT
- Product / population
- BRIVIACT oral tablets/solution and IV injection; age/weight-based epilepsy dosing is separate from this renal finding.
- Renal measure
- Renal function qualitative; source PK prints CrCl in mL/min/1.73 m2
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Selected sections only. A hosted mirror is not independent confirmation of the underlying label.
Renal dosing, restrictions and evidence limits
No renal dose adjustment is required for impaired renal function in the selected source. However, ESRD patients undergoing dialysis lack data and use is not recommended. The severe nondialysis study found increased parent-drug and inactive-metabolite exposure; this is not a dialysis dose schedule.
Hepatic impairment has separate dose modifications. Do not misread the renal statement as an all-population dose clearance or transfer another antiseizure medicine's dialysis replacement dose.