GlobalRPh RX List - Adcetris
- Product / population
- Selected adult IV renal guidance; not a complete oncology regimen.
- Renal measure
- CrCl, mL/min; equation not specified in the selected subsection.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
No renal dose adjustment is recommended for mild impairment (CrCl greater than 50 to 80 mL/min) or moderate impairment (30 to 50 mL/min). Avoid use when CrCl is below 30 mL/min. The source associates severe impairment with increased MMAE exposure and more grade 3 or greater adverse events and deaths. This section does not provide a dialysis regimen.