GlobalRPh RX List - IMURAN
- Product / population
- Oral azathioprine; renal dysfunction in the immediate post-transplant setting.
- Renal measure
- Qualitative oliguria and tubular necrosis; no numeric renal band.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Oliguric patients, particularly those with tubular necrosis immediately after cadaveric transplantation, may clear azathioprine or its metabolites more slowly and are usually given lower doses. The selected section provides no fixed CrCl-based reduction. Do not confuse TPMT/NUDT15 genotype reductions or the transplantation maintenance range with a universal renal-dose table.