GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Amifampridine tablets (FIRDAPSE)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

FIRDAPSE

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Rxlist source

GlobalRPh RX List - FIRDAPSE

Product / population
FIRDAPSE adult and pediatric weight-based starting-dose instructions; daily totals require divided administration.
Renal measure
CrCl 15-90 mL/min as printed.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

At CrCl 15-90 mL/min, use the lowest starting daily total: 15 mg/day for adults and pediatric patients weighing at least 45 kg, or 5 mg/day for pediatric patients under 45 kg. Give in divided doses and titrate to clinical response and tolerability within the complete product schedule. CrCl <15 mL/min and dialysis have not been studied; no dose recommendation is supplied for those settings.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/firdapse-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - FIRDAPSE

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

FIRDAPSE adult and pediatric weight-based starting-dose instructions; daily totals require divided administration.

Renal method: CrCl 15-90 mL/min as printed.
Retrieved: 2026-09-07

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

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Original content / product scopeGlobalRPh RX List - FIRDAPSE
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/firdapse-drug/

Exact product and population

FIRDAPSE adult and pediatric weight-based starting-dose instructions; daily totals require divided administration.

RDM41-SCOPE-amifampridine-firdapse · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - FIRDAPSE

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GlobalRPh-hosted RX List · FIRDAPSE adult and pediatric weight-based starting-dose instructions; daily totals require divided administration.

Renal method: CrCl 15-90 mL/min as printed.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

At CrCl 15-90 mL/min, use the lowest starting daily total: 15 mg/day for adults and pediatric patients weighing at least 45 kg, or 5 mg/day for pediatric patients under 45 kg. Give in divided doses and titrate to clinical response and tolerability within the complete product schedule. CrCl <15 mL/min and dialysis have not been studied; no dose recommendation is supplied for those settings.

RDM41-rxlist-amifampridine-firdapse-5b8047cd60-C1 · Source locator: Dosage / Use in specific populations: renal impairment

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/firdapse-drug/
Retrieved
2026-09-07
Renal-function method
CrCl 15-90 mL/min as printed.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
79ea52eca01dbb2cef747c59dbb441afde3ff15967a815bcd34b1479e00082e6

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/firdapse-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
11274cd219897bce4f71437c8c2ac833044c07f133c097497fe0cc9b2f71b83b
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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