GlobalRPh RX List - KAZANO
- Product / population
- Adult fixed-dose alogliptin/metformin product; not either ingredient alone.
- Renal measure
- eGFR mL/min/1.73 m2.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Contraindicated at eGFR <30. Not recommended at eGFR 30-60 because the fixed combination cannot supply the required lower alogliptin dose. Assess renal function before treatment and periodically. Do not split or borrow a component-only regimen to overcome this product restriction. The selected renal summary is not the complete metformin contrast, acute-illness or lactic-acidosis guidance.