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Cimduo - HHS HIV guidelines panel / ClinicalInfo
Product / population
Adults or adolescents with HIV taking the lamivudine/TDF fixed-dose tablet.
Renal method
Adult CrCl in mL/min; panel has a separate hemodialysis entry.
Source revision
Online guidance checked 2026-11-07; section revision not established.
HHS HIV guidelines panel / ClinicalInfo · Adults or adolescents with HIV taking the lamivudine/TDF fixed-dose tablet.
Renal method: Adult CrCl in mL/min; panel has a separate hemodialysis entry. Source date: Online guidance checked 2026-11-07; section revision not established. Retrieved: 2026-11-07
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
The panel advises avoiding TDF when possible below CrCl 60 mL/min. This lamivudine/TDF fixed combination is not recommended below 50 mL/min or on HD. The ingredient-level TDF interval must not be applied to the fixed tablet.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
