One or two intact local summaries. No averaged regimen, patient-specific dose or automatic source preference.
1 local source card selected. Local card fingerprints checked where supplied. This is not an original-document hash, source-currency guarantee or clinical approval. Record-level cautions below are the current library's cautions, not a frozen prior version.
Independent clinical review is pending. Confirm indication, exact formulation/route, population, renal measure and units, kidney-function stability, dialysis prescription, interacting drugs, monitoring and source revision. An RX mirror and its original label are not independent corroboration. Missing disagreement notes do not certify agreement.
The original page contains two different IV renal band sets (25/50 versus 30/50) and an indexed CrCl table. They are preserved separately, not reconciled into one recommendation. Confirm the applicable current product label before clinical use.
Dialysis recommendations use limited data and expert opinion. The source advises considering an additional post-HD dose. Oral and IV protocols are not interchangeable.
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >25 | 400 mg every 8 hours |
| 10-25 | 400 mg every 8 hours |
| <10 | 200 mg every 12 hours |
| CrCl, mL/min | Source-specific dose / instruction |
|---|---|
| >25 | 800 mg five times daily |
| 10-25 | 800 mg every 8 hours |
| <10 | 400 mg every 12 hours |
| Dialysis setting / indication | Source-specific schedule |
|---|---|
| Intermittent HD - initial/recurrent HSV | 200 mg every 12 hours |
| Intermittent HD - VZV | 400 mg every 12 hours |
| Intermittent HD - suppression/prophylaxis | 200 mg every 12 hours |
| Continuous HD - initial HSV | 400 mg every 8 hours |
| Continuous HD - recurrent HSV or prophylaxis | 400 mg every 12 hours |
| Continuous HD - VZV | 800 mg five times daily |
CrCl >25 / 10-25 / <10 mL/min: initial HSV uses 400 mg orally every 8 hours / 400 mg every 8 hours / 200 mg every 12 hours. Mild VZV uses 800 mg five times daily / 800 mg every 8 hours / 400 mg every 12 hours.
Intermittent HD: initial or recurrent HSV 200 mg every 12 hours; VZV 400 mg every 12 hours; suppression/prophylaxis 200 mg every 12 hours. Continuous HD: initial HSV 400 mg every 8 hours; recurrent HSV 400 mg every 12 hours; VZV 800 mg five times daily; prophylaxis 400 mg every 12 hours.
Dialysis recommendations are based on limited data and expert opinion. The page advises consideration of an additional post-HD dose. Do not transfer these oral regimens to IV acyclovir.
RDM30-034-acyclovir-1 · Source locator: UCSF - oral acyclovir: HSV and VZV; renal/dosing sections and stated qualifiers
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
Pinned reference: https://globalrph.com/blogCalcs/renal-dosing-master/compare.php?id=acyclovir&s1=RDM30-034-acyclovir&h1=fd6ff3d7e75a763404f97f5409bbe698bf1955cb706d52135a91870ed8ad7571