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Silenor - labeled renal guidance
Product / population
Doxepin hydrochloride (Silenor), oral tablet
Renal method
Renal impairment categories as defined by the cited product label
Renal method: Renal impairment categories as defined by the cited product label Source date: DailyMed SPL version 11, posted Apr 24, 2026 Retrieved: 2026-11-07
Pharmacokinetic observation only. A drug-exposure observation is not itself a dose recommendation.
Renal guidance: Prescribing information, renal precautions and clinical pharmacology
Renal impairment was not specifically studied. The label anticipates little change in doxepin exposure because little parent drug or active metabolite is excreted in urine. This observation concerns the low-dose insomnia tablet. It supplies no dialysis replacement schedule.
This reference does not select a regimen. Complete the indication, measured/estimated renal function and trend, dialysis setting, source rationale, monitoring and reassessment plan in your institution's approved documentation system. Confirm the complete current source before adopting its regimen.
GlobalRPh Renal Dosing Master v7.4. Review the retrieval and revision dates attached to each source. Selecting a reference does not imply clinical verification.
